Aberrant neuronal cell cycle re-entry: The pathological confluence of Alzheimer's disease and brain insulin resistance, and its relation to cancer
MM Koseoglu, A Norambuena… - Journal of …, 2019 - content.iospress.com
Aberrant neuronal cell cycle re-entry (CCR) is a phenomenon that precedes and may
mechanistically lead to a majority of the neuronal loss observed in Alzheimer's disease (AD) …
mechanistically lead to a majority of the neuronal loss observed in Alzheimer's disease (AD) …
Baicalin Attenuated Aβ1-42‐Induced Apoptosis in SH‐SY5Y Cells by Inhibiting the Ras‐ERK Signaling Pathway
Z Song, C He, W Yu, M Yang, Z Li, P Li… - BioMed Research …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a serious neurodegenerative disease. It is widely believed that
the accumulation of amyloid beta (Aβ) in neurons around neurofibrillary plaques is the main …
the accumulation of amyloid beta (Aβ) in neurons around neurofibrillary plaques is the main …
[HTML][HTML] MicroRNA networks linked with BRCA1/2, PTEN, and common genes for Alzheimer's disease and breast cancer share highly enriched pathways that may …
MicroRNAs (miRNAs) are involved in the regulation of various cellular processes including
pathological conditions. MiRNA networks have been extensively researched in age-related …
pathological conditions. MiRNA networks have been extensively researched in age-related …
An integrated global analysis of compartmentalized HRAS signaling
Modern omics technologies allow us to obtain global information on different types of
biological networks. However, integrating these different types of analyses into a coherent …
biological networks. However, integrating these different types of analyses into a coherent …
Dexmedetomidine attenuates the toxicity of β‑amyloid on neurons and astrocytes by increasing BDNF production under the regulation of HDAC2 and HDAC5
Y Wang, A Jia, W Ma - Molecular Medicine Reports, 2019 - spandidos-publications.com
Cytotoxicity of β-Amyloid (Aβ) is a major contributor to the pathogenesis of Alzheimer's
disease. Dexmedetomidine (Dex) has been revealed to have multiple neuroprotective …
disease. Dexmedetomidine (Dex) has been revealed to have multiple neuroprotective …
Neuroprotective Effect of S-trans, Trans-farnesylthiosalicylic Acid via Inhibition of RAS/ERK Pathway for the Treatment of Alzheimer's Disease
X Wang, Y Wang, Y Zhu, L Yan… - Drug Design, Development …, 2019 - Taylor & Francis
Background: Alzheimer's disease (AD), a leading cause of dementia, becomes a serious
health issue for individuals and society around the world. AD is a neurodegenerative …
health issue for individuals and society around the world. AD is a neurodegenerative …
Putative factors interfering cell cycle re-entry in Alzheimer's disease: An omics study with differential expression meta-analytics and co-expression profiling
Background: Neuronal cell cycle re-entry (CCR) is a mechanism, along with amyloid-β (Aβ)
oligomers and hyperphosphorylated tau proteins, contributing to toxicity in Alzheimer's …
oligomers and hyperphosphorylated tau proteins, contributing to toxicity in Alzheimer's …