Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix
interactions, growth, proliferation, differentiation, and inflammation. It is not surprising …

Galectins, an ancient lectin family, are characterized by specific binding of β-galactosides
through evolutionary conserved sequence elements of carbohydrate-recognition domain …

The function of deciphering the biological information encoded by the glycome, which is the
entire repertoire of complex sugar structures expressed by cells and tissues, is assigned in …

Galectins, β‐galactoside‐binding animal lectins, are differentially expressed by various
immune cells as well as a wide range of other cell types. Extracellularly, galectins are able to …

Galectins are a family of mammalian β-galactoside-binding proteins that positively and
negatively regulate T cell death. Extracellular galectin-1 directly induces death of T cells and …

In the past decade, increasing efforts have been devoted to the study of galectins, a family of
evolutionarily conserved glycan-binding proteins with multifunctional properties. Galectins …

Inflammation is a critical process for eliminating pathogens, but can lead to serious
deleterious effects if left unchecked. Identifying the endogenous factors that control immune …

Abstract Galectin-3 (Gal-3) is a member of the β-galactoside-binding lectin family and plays
an important role in inflammation. However, the precise role of Gal-3 in autoimmune …

Galectins are a family of animal lectins with affinity for β-galactosides. They are differentially
expressed by various immune cells and their expression levels appear to be dependent on …

Galectin‐3 is absent in resting CD4+ and CD8+ T cells but is inducible by various stimuli.
These include viral transactivating factors, T‐cell receptor (TCR) ligation, and calcium …