Currently, the use of natural gums and mucilage is of increasing importance in
pharmaceutical formulations as valuable drug excipient. Natural plant-based materials are …

In the present investigation, simplex lattice mixture design was applied for formulation
development and optimization of a controlled release dosage form of ketoprofen …

Migraine, one of the neurological conditions, affects approximately 15% of the global
population. It is characterized by intense headaches accompanied by nausea, vomiting, and …

The aim and objective of the present study was to formulate and evaluate controlled release
polymeric tablets of Ibuprofen with determinations of formulation factors using various …

Abstract The dissolution of Active Pharmaceutical Ingredients in polymeric melts plays an
important role in the manufacturing of drugs that use polymers as excipients. The dissolution …

Controlled release formulations are administered once a day and reduce frequency of dose
and ensuring patient's compliance. In the current research controlled release matrices of …

The solubility and dissolution enhancement of the poorly soluble drug ketoprofen (KTO) in
polymer blends prepared by hot melt extrusion was studied using two different screw …

In this work, rifampicin-loaded sodium alginate/chitosan polyelectrolyte microparticles were
prepared by the ionotropic gelation technique using CaCl2 as a cross-linking agent. The …

Dissolution of poorly water-soluble active pharmaceutical ingredients (APIs) in polymeric
melts plays an important role in the manufacturing of solid dispersions and solid solutions …

Preparation of sustained release dosage forms is one of the main objectives in drug
formulation. Tramadol is a centrally acting synthetic opioid analgesic used in treating severe …