BACKGROUND: Mixed cryoglobulinemia is a multisystem disorder associated strongly with
hepatitis C virus (HCV) infection. The kidney frequently is involved, and glomerulonephritis …

In acute hepatitis C virus infection, 50 to 70% of patients develop chronic disease.
Considering the low rate of spontaneous viral clearance during chronic hepatitis C infection …

Several lines of evidence suggest that genetic factors have an important role in the
pathogenesis of immunoglobulin A (IgA) nephropathy. We report the prevalence of familial …

A strong virus‐specific CD4+ and CD8+ T lymphocyte response to hepatitis B virus (HBV)
has been associated with viral clearance, but little is known about factors determining the …

In acute and chronic viral disease the specific response of CD4+ T lymphocytes to certain
viral proteins is an essential part of antiviral effector mechanisms. In hepatitis C virus …

Aims/hypothesis. Islet autoantibodies precede the clinical onset of Type I (insulin-
dependent) diabetes mellitus. The cumulative development of such autoantibodies in infants …

In order to investigate the genetic basis of susceptibility to Henoch–Schoenlein purpura
(HS), blood samples of 152 patients, 105 of whom had renal disease, were collected in a …

OBJECTIVE Description of Greek patients with scleroderma with reference to (a) major
organ disease,(b) autoantibodies,(c) survival rate, and (d) HLA associations. METHODS The …

Background—In β-thalassemia major, heart failure primarily affecting left ventricular systolic
function is the most common complication and cause of death. Apart from iron deposition, it …

Using a human culture system, we have previously shown that interferon-γ-and tumour
necrosis factor-α-stimulated astrocytes are capable of presenting antigens to T lymphocytes …