Tropoelastin and elastin assembly

J Ozsvar, C Yang, SA Cain, C Baldock… - … in bioengineering and …, 2021 - frontiersin.org
Elastic fibers are an important component of the extracellular matrix, providing stretch,
resilience, and cell interactivity to a broad range of elastic tissues. Elastin makes up the …

Elastin architecture

H Vindin, SM Mithieux, AS Weiss - Matrix biology, 2019 - Elsevier
Elastic fibers are an essential component of the extracellular matrix where they provide
structural integrity and elastic recoil in a number of important tissues. A major constituent of …

Conformation of the backbone in unfolded proteins

Z Shi, K Chen, Z Liu, NR Kallenbach - Chemical reviews, 2006 - ACS Publications
Despite its theoretical and practical importance, protein folding remains among the most
fundamental unsolved problems in the life sciences. The challenge of predicting folded …

Structural disorder and dynamics of elastin

LD Muiznieks, AS Weiss… - Biochemistry and Cell …, 2010 - cdnsciencepub.com
Elastin is a self-assembling, extracellular-matrix protein that is the major provider of tissue
elasticity. Here we review structural studies of elastin from over four decades, and draw …

Structural disorder and protein elasticity

S Rauscher, R Pomès - Fuzziness: Structural disorder in protein …, 2012 - Springer
An emerging class of disordered proteins underlies the elasticity of many biological tissues.
Elastomeric proteins are essential to the function of biological machinery as diverse as the …

Structural determinants of cross-linking and hydrophobic domains for self-assembly of elastin-like polypeptides

M Miao, JT Cirulis, S Lee, FW Keeley - Biochemistry, 2005 - ACS Publications
Elastin is a major structural protein found in large blood vessels, lung, ligaments, and skin,
imparting the physical properties of extensibility and elastic recoil to these tissues. To …

Elastin-inspired supramolecular hydrogels: a multifaceted extracellular matrix protein in biomedical engineering

A Sharma, P Sharma, S Roy - Soft Matter, 2021 - pubs.rsc.org
The phenomenal advancement in regenerative medicines has led to the development of
bioinspired materials to fabricate a biomimetic artificial extracellular matrix (ECM) to support …

Investigating by CD the molecular mechanism of elasticity of elastomeric proteins

B Bochicchio, A Pepe… - … , Biological, and Chemical …, 2008 - Wiley Online Library
Elastomeric proteins are widespread in the animal kingdom, and their main function is to
confer elasticity and resilience to organs and tissues. Besides common functional properties …

A synthetic resilin is largely unstructured

KM Nairn, RE Lyons, RJ Mulder, ST Mudie… - Biophysical journal, 2008 - cell.com
Proresilin is the precursor protein for resilin, an extremely elastic, hydrated, cross-linked
insoluble protein found in insects. We investigated the secondary-structure distribution in …

Supramolecular amyloid-like assembly of the polypeptide sequence coded by exon 30 of human tropoelastin

AM Tamburro, A Pepe, B Bochicchio… - Journal of Biological …, 2005 - ASBMB
Elastin is known to self-aggregate in twisted-rope filaments. However, an ultrastructural
organization different from the fibrils typical of elastin, but rather similar to those shown by …