Neonatal immune system ontogeny: the role of maternal microbiota and associated factors. How might the non-human primate model enlighten the path?

N Nunez, L Réot, E Menu - Vaccines, 2021 - mdpi.com
Interactions between the immune system and the microbiome play a crucial role on the
human health. These interactions start in the prenatal period and are critical for the …

The biology of aging in a social world: Insights from free-ranging rhesus macaques

LE Newman, C Testard, AR DeCasien, KL Chiou… - Neuroscience & …, 2023 - Elsevier
Social adversity can increase the age-associated risk of disease and death, yet the
biological mechanisms that link social adversities to aging remain poorly understood. Long …

PLSDA-batch: a multivariate framework to correct for batch effects in microbiome data

Y Wang, KA Lê Cao - Briefings in Bioinformatics, 2023 - academic.oup.com
Microbial communities are highly dynamic and sensitive to changes in the environment.
Thus, microbiome data are highly susceptible to batch effects, defined as sources of …

Gut microbiome composition, not alpha diversity, is associated with survival in a natural vertebrate population

SF Worsley, CS Davies, ME Mannarelli, MI Hutchings… - Animal microbiome, 2021 - Springer
Background The vertebrate gut microbiome (GM) can vary substantially across individuals
within the same natural population. Although there is evidence linking the GM to health in …

Longitudinal gut microbiome dynamics in relation to age and senescence in a wild animal population

SF Worsley, CS Davies, CZ Lee… - Molecular …, 2024 - Wiley Online Library
In humans, gut microbiome (GM) differences are often correlated with, and sometimes
causally implicated in, ageing. However, it is unclear how these findings translate in wild …

PandaGUT provides new insights into bacterial diversity, function, and resistome landscapes with implications for conservation

G Huang, W Shi, L Wang, Q Qu, Z Zuo, J Wang, F Zhao… - Microbiome, 2023 - Springer
Background The gut microbiota play important roles in host adaptation and evolution, but
are understudied in natural population of wild mammals. To address host adaptive evolution …

Ecology, not host phylogeny, shapes the oral microbiome in closely related species

M Moraitou, A Forsythe, JA Fellows Yates… - Molecular biology …, 2022 - academic.oup.com
Host-associated microbiomes are essential for a multitude of biological processes. Placed at
the contact zone between external and internal environments, the little-studied oral …

The long-term gut bacterial signature of a wild primate is associated with a timing effect of pre-and postnatal maternal glucocorticoid levels

S Anzà, D Schneider, R Daniel, M Heistermann… - Microbiome, 2023 - Springer
Background During development, elevated levels of maternal glucocorticoids (GCs) can
have detrimental effects on offspring morphology, cognition, and behavior as well as …

Microbiome variations among age classes and diets of captive Asian elephants (Elephas maximus) in Thailand using full-length 16S rRNA nanopore sequencing

W Klinsawat, P Uthaipaisanwong, P Jenjaroenpun… - Scientific Reports, 2023 - nature.com
Asian elephant (Elephas maximus) is the national symbol of Thailand and linked to Thai
history and culture for centuries. The elephant welfare improvement is one of the major …

Aging gut microbiota of wild macaques are equally diverse, less stable, but progressively personalized

B Sadoughi, D Schneider, R Daniel, O Schülke… - Microbiome, 2022 - Springer
Background Pronounced heterogeneity of age trajectories has been identified as a hallmark
of the gut microbiota in humans and has been explained by marked changes in lifestyle and …