Nitrogenous derivatives of phosphorus and the origins of life: plausible prebiotic phosphorylating agents in water
M Karki, C Gibard, S Bhowmik, R Krishnamurthy - Life, 2017 - mdpi.com
Phosphorylation under plausible prebiotic conditions continues to be one of the defining
issues for the role of phosphorus in the origins of life processes. In this review, we cover the …
issues for the role of phosphorus in the origins of life processes. In this review, we cover the …
Beyond triphosphates: reagents and methods for chemical oligophosphorylation
SM Shepard, HJ Jessen… - Journal of the American …, 2022 - ACS Publications
Oligophosphates play essential roles in biochemistry, and considerable research has been
directed toward the synthesis of both naturally occurring oligophosphates and their synthetic …
directed toward the synthesis of both naturally occurring oligophosphates and their synthetic …
Cyclotriphosphate: A brief history, recent developments, and perspectives in synthesis
D Bezold, T Dürr, J Singh… - Chemistry–A European …, 2020 - Wiley Online Library
There has been a recent upsurge in the study and application of approaches utilizing
cyclotriphosphate 1 (cyclo‐TP, also known as trimetaphosphate, TMP) and/or proceeding …
cyclotriphosphate 1 (cyclo‐TP, also known as trimetaphosphate, TMP) and/or proceeding …
Phosphate esters and anhydrides–recent strategies targeting nature's favoured modifications
Esters and anhydrides of phosphoric acid are essential in biology. It is very difficult to identify
processes in life that do not involve these modifications and their transformation at some …
processes in life that do not involve these modifications and their transformation at some …
Nucleoside tetra-and pentaphosphates prepared using a tetraphosphorylation reagent are potent inhibitors of ribonuclease A
Adenosine and uridine 5′-tetra-and 5′-pentaphosphates were synthesized from an
activated tetrametaphosphate ([PPN] 2 [P4O11],[PPN] 2 [1], PPN= bis (triphenylphosphine) …
activated tetrametaphosphate ([PPN] 2 [P4O11],[PPN] 2 [1], PPN= bis (triphenylphosphine) …
Synthesis of nucleoside triphosphates from 2′-3′-protected nucleosides using trimetaphosphate
S Mohamady, SD Taylor - Organic letters, 2016 - ACS Publications
Chemists have been attempting to triphosphorylate nucleosides and other alcohols using
trimetaphosphate (TriMP) since the 1960s. However, this route appears to have been …
trimetaphosphate (TriMP) since the 1960s. However, this route appears to have been …
How to form a phosphate anhydride linkage in nucleotide derivatives
YV Sherstyuk, TV Abramova - ChemBioChem, 2015 - Wiley Online Library
The fundamental roles of nucleoside triphosphates and nucleotide cofactors such as NAD+
in biochemistry are well known. In recent decades, continuing research has revealed the key …
in biochemistry are well known. In recent decades, continuing research has revealed the key …
Synthesis of α, δ-Disubstituted Tetraphosphates and Terminally-Functionalized Nucleoside Pentaphosphates
SM Shepard, H Kim, QX Bang… - Journal of the …, 2020 - ACS Publications
The anion [P4O11] 2–, employed as its bis (triphenylphosphine) iminium (PPN) salt, is
shown herein to be a versatile reagent for nucleophile tetraphosphorylation. Treatment …
shown herein to be a versatile reagent for nucleophile tetraphosphorylation. Treatment …
Physicochemical aspects of aqueous and nonaqueous approaches to the preparation of nucleosides, nucleotides and phosphate ester mimics
DRW Hodgson - Advances in Physical Organic Chemistry, 2017 - Elsevier
Physicochemical Aspects of Aqueous and Nonaqueous Approaches to the Preparation of
Nucleosides, Nucleotides and Phosphate Ester Mimics - ScienceDirect Skip to main contentSkip …
Nucleosides, Nucleotides and Phosphate Ester Mimics - ScienceDirect Skip to main contentSkip …