Old yellow enzyme-catalysed asymmetric hydrogenation: linking family roots with improved catalysis

A Scholtissek, D Tischler, AH Westphal… - Catalysts, 2017 - mdpi.com
Asymmetric hydrogenation of activated alkenes catalysed by ene-reductases from the old
yellow enzyme family (OYEs) leading to chiral products is of potential interest for industrial …

N-glycolylneuraminic acid as a carbohydrate cancer biomarker

J Wang, LK Shewell, CJ Day, MP Jennings - Translational Oncology, 2023 - Elsevier
One of the forms of aberrant glycosylation in human tumors is the expression of N-
glycolylneuraminic acid (Neu5Gc). The only known enzyme to biosynthesize Neu5Gc in …

Determination of sialic acids in milks and milk-based products

V Spichtig, J Michaud, S Austin - Analytical Biochemistry, 2010 - Elsevier
Sialic acids are becoming recognized as important components of milk-based products for
infants and young children. As such, many companies now label the sialic acid content of …

[HTML][HTML] Serum Neu5Gc biomarkers are elevated in primary cutaneous melanoma

LK Shewell, CJ Day, T Hippolite, X De Bisscop… - Biochemical and …, 2023 - Elsevier
Cutaneous melanoma is one of the most aggressive and deadly types of skin cancer and
rates of disease are continuing to increase worldwide. Currently, no serum biomarkers exist …

Layer-by-layer assembly of composite conductive fiber-based organic electrochemical transistor for highly sensitive detection of sialic acid

R Zhu, Y Wang, Y Tao, Y Wang, Y Chen, M Li, Q Liu… - Electrochimica …, 2022 - Elsevier
A novel composites conductive fiber based on Poly (diallyldimethylammonium chloride) and
multi-walled carbon nanotubes/Poly (3, 4-ethylenedioxythiophene)-Poly (styrenesulfonate) …

Determination of sialic acid and gangliosides in biological samples and dairy products: a review

R Lacomba, J Salcedo, A Alegría, MJ Lagarda… - … of pharmaceutical and …, 2010 - Elsevier
Gangliosides are sphingolipids containing one or more moieties of sialic acid in their
structure. Both gangliosides and sialic acid are bioactive compounds related to animal …

Label-free and sensitive sialic acid biosensor based on organic electrochemical transistors

X Guo, J Liu, F Liu, F She, Q Zheng, H Tang… - Sensors and Actuators B …, 2017 - Elsevier
This work presented a simple, label-free, and selective device for noninvasive cancer cell
identification by sensitive sialic acid (SA) detection using the organic electrochemical …

Diverse properties of the mesothelial cells in health and disease

K Kawanishi - Pleura and peritoneum, 2016 - degruyter.com
Mesothelial cells (MCs) form the superficial anatomic layer of serosal membranes, including
pleura, pericardium, peritoneum, and the tunica of the reproductive organs. MCs produce a …

N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease

LK Shewell, CJ Day, JR Kutasovic, JL Abrahams… - BMC cancer, 2022 - Springer
Background Normal human tissues do not express glycans terminating with the sialic acid N-
glycolylneuraminic acid (Neu5Gc), yet Neu5Gc-containing glycans have been consistently …

β-Cyclodextrin-Tethered Butein, a Greener Redox-Active Biomaterial for Electrochemical Enzymatic Sensing of Sialic Acid

R Kanagaraj, V Krishnan, S Senthil Kumar… - ACS Applied Bio …, 2024 - ACS Publications
Biocompatible, industrially scalable, and opto/electrochemically active biomaterials are
promising for biosensor platform design and application. Herein, cyclic oligosaccharide, β …