Optimization of metabolomic data processing using NOREVA

J Fu, Y Zhang, Y Wang, H Zhang, J Liu, J Tang… - Nature protocols, 2022 - nature.com
A typical output of a metabolomic experiment is a peak table corresponding to the intensity
of measured signals. Peak table processing, an essential procedure in metabolomics, is …

The foundations and development of lipidomics

X Han, RW Gross - Journal of lipid research, 2022 - ASBMB
For over a century, the importance of lipid metabolism in biology was recognized but difficult
to mechanistically understand due to the lack of sensitive and robust technologies for …

To metabolomics and beyond: a technological portfolio to investigate cancer metabolism

F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …

Sustainable management of plastic wastes in COVID-19 pandemic: The biochar solution

AD Igalavithana, X Yuan, CP Attanayake, S Wang… - Environmental …, 2022 - Elsevier
To prevent the COVID-19 transmission, personal protective equipment (PPE) and packaging
materials have been extensively used but often managed inappropriately, generating huge …

Recent review on selected xenobiotics and their impacts on gut microbiome and metabolome

Y Jin, J Chi, K LoMonaco, A Boon, H Gu - TrAC Trends in Analytical …, 2023 - Elsevier
As it is well known, the gut is one of the primary sites in any host for xenobiotics, and the
many microbial metabolites responsible for the interactions between the gut microbiome and …

Single-cell omics: experimental workflow, data analyses and applications

F Sun, H Li, D Sun, S Fu, L Gu, X Shao, Q Wang… - Science China Life …, 2024 - Springer
Cells are the fundamental units of biological systems and exhibit unique development
trajectories and molecular features. Our exploration of how the genomes orchestrate the …

Single-cell mass spectrometry enables insight into heterogeneity in infectious disease

TD Nguyen, Y Lan, SS Kane, JJ Haffner, R Liu… - Analytical …, 2022 - ACS Publications
Cellular heterogeneity is generally overlooked in infectious diseases. In this study, we
investigated host cell heterogeneity during infection with Trypanosoma cruzi (T. cruzi) …

[HTML][HTML] Metabolomics during the spontaneous fermentation in cocoa (Theobroma cacao L.): An exploraty review

CR Balcázar-Zumaeta, EM Castro-Alayo… - Food Research …, 2023 - Elsevier
Spontaneous fermentation is a process that depends on substrates' physical characteristics,
crop variety, and postharvest practices; it induces variations in the metabolites that are …

[HTML][HTML] Toward modeling metabolic state from single-cell transcriptomics

K Hrovatin, DS Fischer, FJ Theis - Molecular Metabolism, 2022 - Elsevier
Background Single-cell metabolic studies bring new insights into cellular function, which can
often not be captured on other omics layers. Metabolic information has wide applicability …

Material-assisted mass spectrometric analysis of low molecular weight compounds for biomedical applications

AS Kulkarni, L Huang, K Qian - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Low molecular weight compounds play an important role in encoding the current
physiological state of an individual. Laser desorption/ionization mass spectrometry (LDI MS) …