Thrombin and vascular inflammation
M Popović, K Smiljanić, B Dobutović, T Syrovets… - Molecular and cellular …, 2012 - Springer
Vascular endothelium is a key regulator of homeostasis. In physiological conditions it
mediates vascular dilatation, prevents platelet adhesion, and inhibits thrombin generation …
mediates vascular dilatation, prevents platelet adhesion, and inhibits thrombin generation …
Small artery remodeling in obesity and insulin resistance
AM Briones, R Aras-Lopez, MJ Alonso… - Current vascular …, 2014 - ingentaconnect.com
Microvascular abnormalities, both in function and structure, lead to impaired tissue perfusion
that may affect multiple tissues and organs and seem to be involved in target-organ damage …
that may affect multiple tissues and organs and seem to be involved in target-organ damage …
Liraglutide attenuates high glucose-induced abnormal cell migration, proliferation, and apoptosis of vascular smooth muscle cells by activating the GLP-1 receptor …
L Shi, Y Ji, X Jiang, L Zhou, Y Xu, Y Li, W Jiang… - Cardiovascular …, 2015 - Springer
Background As a new anti-diabetic medicine, Liraglutide (LIRA), one of GLP-1 analogues,
has been found to have an anti-atherosclerotic effect. Since vascular smooth muscle cells …
has been found to have an anti-atherosclerotic effect. Since vascular smooth muscle cells …
Insulin promotes vascular smooth muscle cell proliferation and apoptosis via differential regulation of tumor necrosis factor‐related apoptosis‐inducing ligand: 胰岛素 …
摘要背景胰岛素不但可以调节葡萄糖平衡, 而且能够促进血管平滑肌(vascular smooth muscle,
VSMC) 的增殖, 它在动脉粥样硬化形成的过程中具有重要的作用. 最近, 我们发现肿瘤坏死因子 …
VSMC) 的增殖, 它在动脉粥样硬化形成的过程中具有重要的作用. 最近, 我们发现肿瘤坏死因子 …
Resveratrol Inhibits Insulin‐Induced Vascular Smooth Muscle Cell Proliferation and Migration by Activating SIRT1
Y Wang, L Lei, Q Su, S Qin, J Zhong… - Evidence‐Based …, 2022 - Wiley Online Library
Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) are essential
for the development of hypertension. Insulin has been identified to promote VSMC …
for the development of hypertension. Insulin has been identified to promote VSMC …
Mercury induces proliferation and reduces cell size in vascular smooth muscle cells through MAPK, oxidative stress and cyclooxygenase-2 pathways
A Aguado, M Galán, O Zhenyukh, GA Wiggers… - Toxicology and applied …, 2013 - Elsevier
Mercury exposure is known to increase cardiovascular risk but the underlying cellular
mechanisms remain undetermined. We analyzed whether chronic exposure to HgCl2 affects …
mechanisms remain undetermined. We analyzed whether chronic exposure to HgCl2 affects …
Heart fat and carotid artery atherosclerosis progression in recently menopausal women: impact of menopausal hormone therapy: The KEEPS trial
SR El Khoudary, V Venugopal, JAE Manson… - Menopause, 2020 - journals.lww.com
Objective: Heart fat deposition has been linked to atherosclerosis, and both accelerate after
menopause. Hormone therapy (HT) may differentially slow heart fat deposition and …
menopause. Hormone therapy (HT) may differentially slow heart fat deposition and …
Protective role of serpina3c as a novel thrombin inhibitor against atherosclerosis in mice
L Qian, J Ji, J Guo, Y Wu, G Ma, Y Yao - Clinical Science, 2021 - portlandpress.com
Abnormal vascular smooth muscle cell (VSMC) proliferation is a critical step in the
development of atherosclerosis. Serpina3c is a serine protease inhibitor (serpin) that plays a …
development of atherosclerosis. Serpina3c is a serine protease inhibitor (serpin) that plays a …
A novel protective function of 5-methoxytryptophan in vascular injury
Methoxytryptophan (5-MTP), a 5-methoxyindole metabolite of tryptophan metabolism, was
recently shown to suppress inflammatory mediator-induced cancer cell proliferation and …
recently shown to suppress inflammatory mediator-induced cancer cell proliferation and …
Insulin resistance is associated with carotid intima-media thickness in non-diabetic subjects. A cross-sectional analysis of the ELSA-Brasil cohort baseline
Background and aims Epidemiological studies have analyzed the association between
carotid intima-media thickness (CIMT) and insulin resistance, glucose levels or glycated …
carotid intima-media thickness (CIMT) and insulin resistance, glucose levels or glycated …