Fungal infection of insects: molecular insights and prospects

S Hong, J Shang, Y Sun, G Tang, C Wang - Trends in Microbiology, 2024 - cell.com
Entomopathogenic fungi (EPF) distribute in different fungal phyla with variable host ranges
and play essential role in regulating insect populations by infecting hosts via cuticle …

The pathobiology of human fungal infections

GD Brown, ER Ballou, S Bates, EM Bignell… - Nature Reviews …, 2024 - nature.com
Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

Immunity to fungi in the lung

LJ Heung, DL Wiesner, K Wang, A Rivera… - Seminars in immunology, 2023 - Elsevier
The respiratory tree maintains sterilizing immunity against human fungal pathogens.
Humans inhale ubiquitous filamentous molds and geographically restricted dimorphic fungal …

Cryptococcus neoformans Infection in the Central Nervous System: The Battle between Host and Pathogen

Y Chen, ZW Shi, AB Strickland, M Shi - Journal of Fungi, 2022 - mdpi.com
Cryptococcus neoformans (C. neoformans) is a pathogenic fungus with a global distribution.
Humans become infected by inhaling the fungus from the environment, and the fungus …

Decoding Toll-like receptors: Recent insights and perspectives in innate immunity

T Kawai, M Ikegawa, D Ori, S Akira - Immunity, 2024 - cell.com
Toll-like receptors (TLRs) are an evolutionarily conserved family in the innate immune
system and are the first line of host defense against microbial pathogens by recognizing …

[HTML][HTML] Fungal effectors: Past, present, and future

G Li, M Newman, H Yu, M Rashidzade… - Current Opinion in …, 2024 - Elsevier
Highlights•Fungi can be symbionts and pathogens of both plant and animal hosts.•Fungal
effectors are key players involved in all host–fungal interactions.•Apoplastic or cytoplasmic …

Understanding the development of Th2 cell-driven allergic airway disease in early life

B León - Frontiers in Allergy, 2023 - frontiersin.org
Allergic diseases, including atopic dermatitis, allergic rhinitis, asthma, and food allergy, are
caused by abnormal responses to relatively harmless foreign proteins called allergens …

Exploiting antifungal immunity in the clinical context

MS Lionakis - Seminars in immunology, 2023 - Elsevier
The continuous expansion of immunocompromised patient populations at-risk for
developing life-threatening opportunistic fungal infections in recent decades has helped …

Fungal mechanisms of intracellular survival: what can we learn from bacterial pathogens?

PV Stuckey, FH Santiago-Tirado - Infection and Immunity, 2023 - Am Soc Microbiol
Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1

G Luo, J Zhang, T Wang, H Cui, Y Bai, J Luo, J Zhang… - Cell Host & Microbe, 2024 - cell.com
Candida albicans stably colonizes humans but is the leading cause of hospital-acquired
fungemia. Traditionally, masking immunogenic moieties has been viewed as a tactic for …