Summary In 2013, a Lancet Infectious Diseases Commission described the state of
antimicrobial resistance worldwide. Since then, greater awareness of the public health …

Introduction Antimicrobial resistance (AMR) is a concern as this increases morbidity,
mortality, and costs, with sub-Saharan Africa having the highest rates globally. Concerns …

Antimicrobial resistance (AMR) poses a serious threat to human, animal and environmental
health worldwide. Colistin has regained importance as a last-resort treatment against multi …

There are serious concerns with rising antimicrobial resistance (AMR) across countries
increasing morbidity, mortality and costs. These concerns have resulted in a plethora of …

Colistin is the last-resort antibiotic to treat multidrug-resistant (MDR) Gram-negative bacterial
infections that are untreatable by other clinically available antibiotics. However, the recently …

Introduction: Antibiotics are indispensable to maintaining human health; however, their
overuse has resulted in resistant organisms, increasing morbidity, mortality and costs …

Objectives: In line with the recent global action plan for antimicrobial resistance, this is the
first time such a comprehensive antimicrobial point prevalence survey has been undertaken …

Objective: There is an urgent need to undertake Point Prevalence Surveys (PPS) across
Africa to document antimicrobial utilisation rates given high rates of infectious diseases and …

There are concerns with the current prescribing of antibiotics in both the private and public
primary care settings in South Africa. These concerns need to be addressed going forward …

Mobile colistin resistance (mcr) genes (mcr-1 to mcr-10) are plasmid-encoded genes that
threaten the clinical utility of colistin (COL), one of the highest-priority critically important …