Carbonic anhydrases (CAs, EC 4.2. 1.1) are ubiquitous metallo-enzymes, present
throughout most living organisms and encoded by five evolutionarily unrelated gene …

Human carbonic anhydrase (CA) IX is a tumor‐associated protein, since it is scarcely
present in normal tissues, but highly overexpressed in a large number of solid tumors, where …

Nature takes advantage of the pervasive presence of water to control many enzymatic
reactions by utilizing the unique properties of water, which in turn help regulating reaction …

Why metalloenzymes often show dramatic changes in their catalytic activity when subjected
to chemically similar but non-native metal substitutions is a long-standing puzzle. Here, we …

Solvent structures that surround active sites reorganize during catalysis and influence the
stability of surface intermediates. Within zeolite pores, H2O molecules form hydrogen …

Carbonic anhydrase (CA, EC 4.2. 1.1) is a protein that is especially well-suited to serve as a
model in many types of studies in biophysics, bioanalysis, the physical-organic chemistry of …

An overview of applications of the recently developed gauge including magnetically induced
current method (GIMIC) is presented. The GIMIC method is used to obtain magnetically …

Catalytic reactions involve the direct interaction of reactants, intermediates and products with
the catalyst surface. We not only need to control the atomic structure and electronic …

The carbonic anhydrases enzymes (CAs, EC 4.2. 1.1) are zinc containing metalloproteins,
which efficiently catalyse the reversible conversion of carbon dioxide to bicarbonate and …

Voltage-gated proton channels (HV) are unique, in part because the ion they conduct is
unique. HV channels are perfectly selective for protons and have a very small unitary …