Systemic autoimmune diseases are characterized by the failure of the immune system to
differentiate self from non-self. These conditions are associated with significant morbidity …

Neutrophils are the first responders to infection and inflammation and are thus a critical
component of innate immune defense. Understanding the behavior of neutrophils as they …

Neutrophils accumulate in solid tumors, and their abundance correlates with poor prognosis.
Neutrophils are not homogeneous, however, and could play different roles in cancer …

In recent years, neutrophils have attracted increasing attention because of their cancer-
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …

Neutrophils are the most abundant myeloid cells in human blood and are emerging as
important regulators of cancer. However, their functional importance has often been …

Non-small cell lung cancer (NSCLC) is characterized by molecular heterogeneity with
diverse immune cell infiltration patterns, which has been linked to therapy sensitivity and …

Neutrophils play a key role in defence against infection and in the activation and regulation
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …

Blood myeloid cells are known to be dysregulated in coronavirus disease 2019 (COVID-19),
caused by SARS-CoV-2. It is unknown whether the innate myeloid response differs with …

There is an urgent need to better understand the pathophysiology of Coronavirus disease
2019 (COVID-19), the global pandemic caused by SARS-CoV-2, which has infected more …

SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …