Malaria is one of the most devastating human infectious diseases caused by Plasmodium
spp. parasites. A search for an effective and safe vaccine is the main challenge for its …

Viral nanotechnology exploits the prefabricated nanostructures of viruses, which are already
abundant in nature. With well-defined molecular architectures, viral nanocarriers offer …

Plasmodium sporozoites are transmitted from infected mosquitoes to mammals, and must
navigate the host skin and vasculature to infect the liver. This journey requires distinct …

The study of antigenic targets of naturally-acquired immunity is essential to identify and
prioritize antigens for further functional characterization. We measured total IgG antibodies …

Introduction Plasmodium vivax causes significant public health problems in endemic
regions. A vaccine to prevent disease is critical, considering the rapid spread of drug …

In Plasmodium vivax, the most studied vaccine antigens are aimed at blocking merozoite
invasion of erythrocytes and disease development. Very few studies have evaluated pre …

Plasmodium vivax pre-erythrocytic (PE) vaccine research has lagged far behind efforts to
develop Plasmodium falciparum vaccines. There is a critical gap in our knowledge of PE …

Malaria is a highly prevalent parasitic disease in regions with tropical and subtropical
climates worldwide. Among the species of Plasmodium causing human malaria, P. vivax is …

CelTOS is a malaria vaccine antigen that is conserved in Plasmodium and other
apicomplexan parasites and plays a role in cell-traversal. The structural basis and …

Introduction: Transgenic malaria parasites expressing foreign genes, for example
fluorescent and luminescent proteins, are used extensively to interrogate parasite biology …