Depression in type 2 diabetes mellitus: prevalence, impact, and treatment

K Semenkovich, ME Brown, DM Svrakic, PJ Lustman - Drugs, 2015 - Springer
Clinically significant depression is present in one of every four people with type 2 diabetes
mellitus (T2DM). Depression increases the risk of the development of T2DM and the …

Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile

BWJH Penninx, Y Milaneschi, F Lamers, N Vogelzangs - BMC medicine, 2013 - Springer
Depression is the most common psychiatric disorder worldwide. The burden of disease for
depression goes beyond functioning and quality of life and extends to somatic health …

Air pollution, stress, and allostatic load: linking systemic and central nervous system impacts

EM Thomson - Journal of Alzheimer's Disease, 2019 - content.iospress.com
Air pollution is a risk factor for cardiovascular and respiratory morbidity and mortality. A
growing literature also links exposure to diverse air pollutants (eg, nanoparticles, particulate …

HPA axis and aging in depression: systematic review and meta-analysis

MB Murri, C Pariante, V Mondelli, M Masotti… - …, 2014 - Elsevier
One of the most consistent findings in the biology of depression is an altered activity of the
hypothalamic–pituitary–adrenal (HPA) axis. However, data concerning this issue have never …

Pathways linking late-life depression to persistent cognitive impairment and dementia

MA Butters, JB Young, O Lopez… - Dialogues in clinical …, 2008 - Taylor & Francis
There is a strong association between late-life depression, cognitive impairment,
cerebrovascular disease, and poor cognitive outcomes, including progressive dementia …

Metabolic consequences of stress during childhood and adolescence

P Pervanidou, GP Chrousos - Metabolism, 2012 - Elsevier
Stress, that is, the state of threatened or perceived as threatened homeostasis, is associated
with activation of the stress system, mainly comprised by the hypothalamic-pituitary-adrenal …

Sympathetic nervous activation in obesity and the metabolic syndrome—causes, consequences and therapeutic implications

GW Lambert, NE Straznicky, EA Lambert… - Pharmacology & …, 2010 - Elsevier
The world wide prevalence of obesity and the metabolic syndrome is escalating. Contrary to
earlier experimental evidence, human obesity is characterised by sympathetic nervous …

The relationship between depression and risk of metabolic syndrome: a meta‐analysis of observational studies

Y Moradi, AN Albatineh, H Mahmoodi… - Clinical diabetes and …, 2021 - Springer
Introduction The link between metabolic syndrome and depression has always been
controversial. Different studies that have examined the relationship between metabolic …

Depression gets old fast: do stress and depression accelerate cell aging?

OM Wolkowitz, ES Epel, VI Reus… - Depression and …, 2010 - Wiley Online Library
Depression has been likened to a state of “accelerated aging,” and depressed individuals
have a higher incidence of various diseases of aging, such as cardiovascular and …

Anxiety and depression among outpatients with type 2 diabetes: A multi-centre study of prevalence and associated factors

AK Khuwaja, S Lalani, R Dhanani, IS Azam… - Diabetology & metabolic …, 2010 - Springer
Background Anxiety and depression contribute to poor disease outcomes among individuals
with diabetes. This study aimed to assess the prevalence of anxiety and depression and to …