Neural modulation with photothermally active nanomaterials

Y Wang, R Garg, D Cohen-Karni… - Nature Reviews …, 2023 - nature.com
Modulating neural electrophysiology with high precision is essential for understanding
neural communication and for the diagnosis and treatment of neural disorders. Photothermal …

Emerging bioelectronics for brain organoid electrophysiology

K Tasnim, J Liu - Journal of molecular biology, 2022 - Elsevier
Human brain organoids are generated from three-dimensional (3D) cultures of human
induced pluripotent stem cells and embryonic stem cells, which partially replicate the …

Shell microelectrode arrays (MEAs) for brain organoids

Q Huang, B Tang, JC Romero, Y Yang, SK Elsayed… - Science …, 2022 - science.org
Brain organoids are important models for mimicking some three-dimensional (3D)
cytoarchitectural and functional aspects of the brain. Multielectrode arrays (MEAs) that …

Stretchable mesh nanoelectronics for 3D single‐cell chronic electrophysiology from developing brain organoids

P Le Floch, Q Li, Z Lin, S Zhao, R Liu… - Advanced …, 2022 - Wiley Online Library
Human induced pluripotent stem cell derived brain organoids have shown great potential for
studies of human brain development and neurological disorders. However, quantifying the …

The e-Flower: A hydrogel-actuated 3D MEA for brain spheroid electrophysiology

E Martinelli, O Akouissi, L Liebi, I Furfaro, D Maulà… - Science …, 2024 - science.org
Traditional microelectrode arrays (MEAs) are limited to measuring electrophysiological
activity in two dimensions, failing to capture the complexity of three-dimensional (3D) tissues …

First Organoid Intelligence (OI) workshop to form an OI community

IE Morales Pantoja, L Smirnova, AR Muotri… - Frontiers in Artificial …, 2023 - frontiersin.org
The brain is arguably the most powerful computation system known. It is extremely efficient
in processing large amounts of information and can discern signals from noise, adapt, and …

Humanized brain organoids-on-chip integrated with sensors for screening neuronal activity and neurotoxicity

P Saglam-Metiner, E Yildirim, C Dincer, O Basak… - Microchimica Acta, 2024 - Springer
The complex structure and function of the human central nervous system that develops from
the neural tube made in vitro modeling quite challenging until the discovery of brain …

Self‐Folding Graphene‐Based Interface for Brain‐Like Modular 3D Tissue

K Sakai, TF Teshima, T Goto… - Advanced Functional …, 2023 - Wiley Online Library
Electrophysiology of 3D neuronal cultures is of rapidly growing importance for revealing
cellular communications associated with neurodevelopment and neurological diseases in …

Organoid intelligence for developmental neurotoxicity testing

DM Alam El Din, J Shin, A Lysinger, MJ Roos… - Frontiers in Cellular …, 2024 - frontiersin.org
The increasing prevalence of neurodevelopmental disorders has highlighted the need for
improved testing methods to determine developmental neurotoxicity (DNT) hazard for …

Protruding cantilever microelectrode array to monitor the inner electrical activity of cerebral organoids

O Phouphetlinthong, E Partiot, C Bernou, A Sebban… - Lab on a Chip, 2023 - pubs.rsc.org
Stem cell-derived cerebral organoids are artificially grown miniature organ-like structures
mimicking embryonic brain architecture. They are composed of multiple neural cell types …