Chronic wasting disease in Europe: new strains on the horizon

MA Tranulis, D Gavier-Widén, J Våge… - Acta Veterinaria …, 2021 - Springer
Prion diseases are fatal neurodegenerative disorders with known natural occurrence in
humans and a few other mammalian species. The diseases are experimentally …

Cervid prion protein polymorphisms: role in chronic wasting disease pathogenesis

MI Arifin, S Hannaoui, SC Chang, S Thapa… - International journal of …, 2021 - mdpi.com
Chronic wasting disease (CWD) is a prion disease found in both free-ranging and farmed
cervids. Susceptibility of these animals to CWD is governed by various exogenous and …

Chronic wasting disease in cervids: prevalence, impact and management strategies

NA Rivera, AL Brandt, JE Novakofski… - Veterinary Medicine …, 2019 - Taylor & Francis
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) that
affects members of the cervidae family. The infectious agent is a misfolded isoform (PrPSC) …

[HTML][HTML] Novel type of chronic wasting disease detected in moose (Alces alces), Norway

L Pirisinu, L Tran, B Chiappini, I Vanni… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
Chronic wasting disease (CWD) persists in cervid populations of North America and in 2016
was detected for the first time in Europe in a wild reindeer in Norway. We report the detection …

Heterogeneity of pathological prion protein accumulation in the brain of moose (Alces alces) from Norway, Sweden and Finland with chronic wasting disease

D Sola, L Tran, J Våge, K Madslien, TT Vuong… - Veterinary …, 2023 - Springer
Prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that
affect several animal species. They are characterized by the conformational conversion of …

Emergence of CWD strains

A Otero, C Duque Velasquez, D McKenzie… - Cell and Tissue …, 2023 - Springer
Chronic wasting disease (CWD) strains present a novel challenge to defining and mitigating
this contagious prion disease of deer, elk, moose, and reindeer. Similar to strains of other …

Review on PRNP genetics and susceptibility to chronic wasting disease of Cervidae

K Moazami-Goudarzi, O Andréoletti, JL Vilotte… - Veterinary …, 2021 - Springer
To date, chronic wasting disease (CWD) is the most infectious form of prion disease affecting
several captive, free ranging and wild cervid species. Responsible for marked population …

Update on chronic wasting disease (CWD) III

EFSA Panel on Biological Hazards (BIOHAZ)… - EFSA …, 2019 - Wiley Online Library
Abstract The European Commission asked EFSA for a Scientific Opinion: to revise the state
of knowledge about the differences between the chronic wasting disease (CWD) strains …

Monitoring of chronic wasting disease (CWD)(IV)

EFSA Panel on Biological Hazards (BIOHAZ)… - EFSA …, 2023 - Wiley Online Library
Abstract The European Commission requested an analysis of the Chronic Wasting Disease
(CWD) monitoring programme in Norway, Sweden, Finland, Iceland, Estonia, Latvia …

Inter-and intra-species conversion efficacies of Norwegian prion isolates estimated by serial protein misfolding cyclic amplification

E Harpaz, TT Vuong, L Tran, MA Tranulis… - Veterinary …, 2023 - Springer
Prion diseases, including chronic wasting disease (CWD) in cervids, are fatal
neurodegenerative disorders caused by the misfolding of cellular prion proteins. CWD is …