Erythropoiesis is a highly regulated process where sequential events ensure the proper
differentiation of hematopoietic stem cells into, ultimately, red blood cells (RBCs) …

ERYTHROPOIETIN (EP) is a glycoprotein produced primarily by the kidney, and is the
principal factor regulating red blood cell (RBC) production. 1 Unlike most of the …

Improved understanding of the inflammatory response and the identification and
characterization of the specific cytokines involved, as well as improved understanding of …

Erythropoiesis is a tightly-regulated and complex process originating in the bone marrow
from a multipotent stem cell and terminating in a mature, enucleated erythrocyte. Altered red …

Erythroblastic islands, the specialized niches in which erythroid precursors proliferate,
differentiate, and enucleate, were first described 50 years ago by analysis of transmission …

Erythropoietin (EPO) is a glycoprotein cytokine known for its pleiotropic effects on various
types of cells and tissues. EPO and its receptor EPOR trigger signaling cascades …

New sources of red blood cells (RBCs) would improve the transfusion capacity of blood
centers. Our objective was to generate cells for transfusion by inducing a massive …

Title: Rossi's principles of transfusion medicine/edited by Toby L. Simon, Eric A. Gehrie,
Jeffrey McCullough, John D. Roback, Edward L. Snyder. Other titles: Principles of …

Macrophages, named for their phagocytic ability, participate in homeostasis, tissue
regeneration and inflammatory responses. Bone and adjacent marrow contain multiple …

Erythroblastic islands are specialized microenvironmental compartments within which
definitive mammalian erythroblasts proliferate and differentiate. These islands consist of a …