Mammary synthesis of milk fat continues to be an active research area, with significant
advances in the regulation of lipid synthesis by bioactive fatty acids (FAs). The …

Peroxisome proliferator activated receptor gamma (PPARγ) is a ligand-dependent
transcription factor and a member of the nuclear receptor superfamily. Acting as sensors of …

Conjugated linoleic acid (CLA), a family of fatty acids found in beef, dairy foods and dietary
supplements, reduces adiposity in several animal models of obesity and some human …

Essential AA (EAA), particularly leucine, isoleucine, methionine, and histidine, possess
signaling properties for promoting cellular anabolic metabolism, whereas methionine, lysine …

The eIF2α phosphorylation-dependent integrated stress response (ISR) is a signaling
pathway that maintains homeostasis in mammalian cells exposed to various stresses. Here …

Objective. To summarize the recent studies on effect of conjugated linoleic acid (CLA) on
hepatic steatosis and hepatic and adipose lipid metabolism highlighting the potential …

It has previously been established that supplementation of trans-10, cis-12 18: 2 reduces
milk fat content and fat deposition in several species. The objectives of the study were 1) to …

Inflammation plays a role in trans-10, cis-12 (10, 12)-conjugated linoleic acid (CLA)-
mediated delipidation and insulin resistance in adipocytes. Given the anti-inflammatory role …

Understanding the mechanistic basis of transcriptional regulation has been a central focus
of molecular biology since its inception. New high-throughput chromatin …

Obesity is the most widespread nutritional disease in the United States. Developing effective
and safe strategies to manage excess body weight is therefore of paramount importance …