Harnessing exosomes as therapeutic drug delivery vehicles requires a better understanding
of exosomal composition and their mode of action. A full appreciation of all the exosomal …

Ca2+ is a universal signalling molecule involved in regulating cell cycle and fate,
metabolism and structural integrity, motility and volume. Like other cells, red blood cells …

Elevated hematocrit is associated with cardiovascular risk; however, the causality and
mechanisms are unclear. The JAK2V617F (Jak2VF) mutation increases cardiovascular risk …

Suicidal death of erythrocytes, or eryptosis, is characterized by cell shrinkage and cell
membrane scrambling leading to phosphatidylserine exposure at the cell surface. Eryptosis …

As cancer poses a significant threat to the well-being of humans on a global scale, many
researchers have embarked on the search for effective anticancer therapeutic agents. In …

Suicidal erythrocyte death (eryptosis) is characterized by cell shrinkage, cell membrane
blebbing, and cell membrane phospholipid scrambling with phosphatidylserine exposure at …

Recently, red blood cell-derived extracellular vesicles (RBCEVs) have attracted attention for
clinical applications because of their safety and biocompatibility. RBCEVs can escape …

The review briefly summaries main features of extracellular vesicles, a joint terminology for
exosomes, microvesicles, and apoptotic vesicles. These vesicles are in the center of interest …

Background Red blood cell–derived microparticles (RMP s) are small phospholipid vesicles
shed from RBCs in blood units, where they accumulate during storage. Because …

Background During storage detrimental biochemical and biomechanical changes occur
within a red blood cell (RBC). RBC microparticles (RMPs) produced during storage have …