Carbon dots: biomacromolecule interaction, bioimaging and nanomedicine

Z Peng, X Han, S Li, AO Al-Youbi… - Coordination chemistry …, 2017 - Elsevier
Carbon dots, a recent member of the renowned carbon-based nanomaterials family, have
attracted significant interest from various fields. The extraordinary properties, including …

Skeletal biology and disease modeling in zebrafish

K Dietrich, IAK Fiedler, A Kurzyukova… - Journal of Bone and …, 2020 - academic.oup.com
Zebrafish are teleosts (bony fish) that share with mammals a common ancestor belonging to
the phylum Osteichthyes, from which their endoskeletal systems have been inherited …

Using zebrafish in systems toxicology for developmental toxicity testing

Y Nishimura, A Inoue, S Sasagawa… - Congenital …, 2016 - Wiley Online Library
With the high cost and the long‐term assessment of developmental toxicity testing in
mammals, the vertebrate zebrafish has become a useful alternative model organism for high …

Transgenic fluorescent zebrafish lines that have revolutionized biomedical research

CP Choe, SY Choi, Y Kee, MJ Kim, SH Kim… - Laboratory Animal …, 2021 - Springer
Since its debut in the biomedical research fields in 1981, zebrafish have been used as a
vertebrate model organism in more than 40,000 biomedical research studies. Especially …

Zebrafish craniofacial development: a window into early patterning

L Mork, G Crump - Current topics in developmental biology, 2015 - Elsevier
The formation of the face and skull involves a complex series of developmental events
mediated by cells derived from the neural crest, endoderm, mesoderm, and ectoderm …

Zebrafish models of human skeletal disorders: embryo and adult swimming together

M Carnovali, G Banfi, M Mariotti - BioMed Research …, 2019 - Wiley Online Library
Danio rerio (zebrafish) is an elective model organism for the study of vertebrate
development because of its high degree of homology with human genes and organs …

Understanding idiopathic scoliosis: a new zebrafish school of thought

CW Boswell, B Ciruna - Trends in Genetics, 2017 - cell.com
Idiopathic scoliosis (IS) refers to a 3D rotation of the spine that occurs in the absence of
underlying vertebral anomalies or obvious physiological defects. Despite affecting …

[HTML][HTML] Advancing toxicology research using in vivo high throughput toxicology with small fish models

A Planchart, CJ Mattingly, D Allen, P Ceger, W Casey… - Altex, 2016 - ncbi.nlm.nih.gov
Small freshwater fish models, especially zebrafish, offer advantages over traditional rodent
models, including low maintenance and husbandry costs, high fecundity, genetic diversity …

Zebrafish models of craniofacial malformations: interactions of environmental factors

ST Raterman, JR Metz, FA Wagener… - Frontiers in Cell and …, 2020 - frontiersin.org
The zebrafish is an appealing model organism for investigating the genetic (G) and
environmental (E) factors, as well as their interactions (GxE), which contribute to craniofacial …

The mechanical impact of col11a2 loss on joints; col11a2 mutant zebrafish show changes to joint development and function, which leads to early-onset osteoarthritis

EA Lawrence, E Kague, JA Aggleton… - … of the Royal …, 2018 - royalsocietypublishing.org
Collagen is the major structural component of cartilage, and mutations in the genes
encoding type XI collagen are associated with severe skeletal dysplasias …