Peptides represent an important class of biologically active molecules with high potential for
the development of diagnostic and therapeutic agents due to their structural diversity …

Triazoles represent a class of heterocycles with interesting properties for application in
peptide sciences since they closely resemble amide bonds while being stable to enzymatic …

Since the discovery of CuI-catalysed click chemistry, the field of peptidomimetics has
expanded to include 1, 4-connected 1, 2, 3-triazoles as useful peptide bond isosteres. Here …

A proper copper catalyst with a chiral pyridine-2, 6-bisoxazoline (pybox) ligand was used to
convert a variety of propargylic acetates with different side chains (R= Ar, Bn, Alkyl) into their …

The gold‐catalyzed enantioselective hydroazidation and hydroamination reactions of
allenes are presented herein. ADC gold (I) catalysts derived from BINAM were critical for …

A copper catalyst with a chiral pyridine‐2, 6‐bisoxazoline (pybox) ligand was used to
convert a variety of propargylic esters with different side chains (R= Ar, Bn, alkyl) into their …

Esters and amides undergo reduction to the corresponding aldehydes using DIBAL-H
followed by same pot conversion to terminal alkynes utilizing the Bestmann–Ohira reagent …

During the last decade α‐amino aldehydes have attracted widespread attention as the
important natural source of chiral substrates useful in stereocontrolled organic synthesis …

This review presents the recent research in biocatalysis and biotransformation in Brazil.
Several substrates were biotransformed by fungi, bacteria and plants. Biocatalytic …

The macrocyclization of linear peptides is very often accompanied by significant
improvements in their stability and biological activity. Many strategies are available for their …