Chlorinated persistent organic pollutants, obesity, and type 2 diabetes

DH Lee, M Porta, DR Jacobs Jr… - Endocrine …, 2014 - academic.oup.com
Persistent organic pollutants (POPs) are lipophilic compounds that travel with lipids and
accumulate mainly in adipose tissue. Recent human evidence links low-dose POPs to an …

Ten years of mixing cocktails: a review of combination effects of endocrine-disrupting chemicals

A Kortenkamp - Environmental health perspectives, 2007 - ehp.niehs.nih.gov
In the last 10 years, good evidence has become available to show that the combined effects
of endocrine disruptors (EDs) belonging to the same category (eg, estrogenic …

EDCs mixtures: a stealthy hazard for human health?

E Ribeiro, C Ladeira, S Viegas - Toxics, 2017 - mdpi.com
Endocrine disrupting chemicals (EDCs) are exogenous chemicals that may occur naturally
(eg, phytoestrogens), while others are industrial substances and plasticizers commonly …

Uncertainties for endocrine disrupters: our view on progress

GP Daston, JC Cook, RJ Kavlock - Toxicological Sciences, 2003 - academic.oup.com
The hypothesis that hormonally active compounds in the environment—endocrine disrupters—
are having a significant impact on human and ecological health has captured the public's …

Mixture effects of endocrine disrupting compounds in vitro

MB Kjærstad, C Taxvig, HR Andersen… - … Journal of Andrology, 2010 - Wiley Online Library
Four different equi‐molar mixtures were investigated for additive endocrine disrupting effects
in vitro using the concentration addition model. It was found that additive effects on the same …

Sensitivity of the immature rat uterotrophic assay to mixtures of estrogens.

H Tinwell, J Ashby - Environmental Health Perspectives, 2004 - ehp.niehs.nih.gov
We have evaluated whether mixtures of estrogens, present in the mix at doses that are
individually inactive in the immature rat uterotrophic assay, can give a uterotrophic …

A Brief Insight into the Toxicity Conundrum: Modeling, Measuring, Monitoring and Evaluating Ecotoxicity for Water Quality towards Environmental Sustainability

P Vilela, G Jácome, W Moya, P Ifaei, S Heo, C Yoo - Sustainability, 2023 - mdpi.com
In view of the continuous increment of industrial residues, the risk associated with chemical
toxicity in the environment has piqued the interest of researchers in pursuit of an alternative …

Estrogenic compounds: chemical characteristics, detection methods, biological and environmental effects

MT Pamplona-Silva, DEC Mazzeo, J Bianchi… - Water, Air, & Soil …, 2018 - Springer
Several chemical compounds are being studied for their capacities to cause imbalances in
several biological systems. Some of those are able to affect the endocrine system and are …

Synergistic interaction of endocrine‐disrupting chemicals: Model development using an ecdysone receptor antagonist and a hormone synthesis inhibitor

X Mu, GA Leblanc - Environmental Toxicology and Chemistry …, 2004 - Wiley Online Library
Endocrine toxicants can interfere with hormone signaling through various mechanisms.
Some of these mechanisms are interrelated in a manner that might result in synergistic …

Estrogenicity of captive southern white rhinoceros diets and their association with fertility

CW Tubbs, LA Moley, JA Ivy, LC Metrione… - General and …, 2016 - Elsevier
The captive southern white rhinoceros (SWR) population is not currently self-sustaining,
primarily due to poor or absent reproduction of captive-born (F 1+) females. In this study, we …