MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene
expression. Alteration in miRNA expression results in changes in the profile of genes …

Importance Thyroid nodules are common, being detected in up to 65% of the general
population. This is likely due to the increased use of diagnostic imaging for purposes …

Importance Approximately 20% of fine-needle aspirations (FNA) of thyroid nodules have
indeterminate cytology, most frequently Bethesda category III or IV. Diagnostic surgeries can …

The discovery of miRNAs in the mid-90s has changed the dogma of gene expression
regulation. Currently, miRNAs are the main theme of thousands of publications each year …

Population-based studies have demonstrated that an increasing number of incidental
thyroid nodules are being identified. The corresponding increase in thyroid-based …

The previous edition of The Bethesda System for Reporting Thyroid Cytopathology provided
important updates and advances in the practice of thyroid cytopathology. It was inspired by …

It has been almost two decades since the first link between microRNAs and cancer was
established. In the ensuing years, this abundant class of short noncoding regulatory RNAs …

Simple Summary Tumor biomarkers are molecules at genetic or protein level, or certain
evaluable characteristics. These help in perfecting patient management. Over the past …

Background Molecular tests are being used increasingly as an auxiliary diagnostic tool so
as to avoid a diagnostic surgery approach for cytologically indeterminate thyroid nodules …

Objective: To describe the evolution and clinical utility of molecular testing for thyroid
nodules and cancer achieved over the last 2 decades. Methods: Scientific reports on thyroid …