Magnetic resonance imaging-guided laser interstitial thermal therapy for the treatment of hypothalamic hamartomas: a retrospective review

DS Xu, T Chen, RJ Hlubek, RE Bristol, KA Smith… - …, 2018 - journals.lww.com
BACKGROUND: Hypothalamic hamartomas (HH) are rare lesions associated with treatment-
resistant epilepsy. Open surgery results in modest seizure control (about 50%) but has a …

Safety and efficacy of Gamma Knife radiosurgery in hypothalamic hamartomas with severe epilepsies: A prospective trial in 48 patients and review of the literature

J Regis, M Lagmari, R Carron, M Hayashi… - …, 2017 - Wiley Online Library
Epilepsies associated with hypothalamic hamartomas (HHs) are frequently drug resistant
with severe psychiatric and cognitive comorbidities. We performed a prospective trial to …

Stereo electroencephalography–guided radiofrequency thermocoagulation (SEEG‐guided RF‐TC) in drug‐resistant focal epilepsy: Results from a 10‐year …

P Bourdillon, J Isnard, H Catenoix, A Montavont… - …, 2017 - Wiley Online Library
Objective Stereo electroencephalography (SEEG)–guided radiofrequency
thermocoagulation (SEEG‐guided RF‐TC) has been proposed since 2004 as a possible …

MR-guided laser ablation for the treatment of hypothalamic hamartomas

DJ Curry, J Raskin, I Ali, AA Wilfong - Epilepsy research, 2018 - Elsevier
Hypothalamic hamartoma is an archetypal example of subcortical epilepsy that can be
associated with intractable gelastic epilepsy, secondary epilepsy, and epileptic …

Hypothalamic hamartomas: optimal approach to clinical evaluation and diagnosis

AA Wilfong, DJ Curry - Epilepsia, 2013 - Wiley Online Library
Hypothalamic hamartomas (HH s) present a difficult medical problem, manifested by gelastic
seizures, which are often medically intractable. Although existing techniques offer modest …

Surgical treatment of hypothalamic hamartomas

P Bourdillon, S Ferrand-Sorbet, C Apra, M Chipaux… - Neurosurgical …, 2021 - Springer
Hypothalamic hamartomas are aberrant masses, composed of abnormally distributed
neurons and glia. Along endocrine and cognitive symptoms, they may cause epileptic …

Laser interstitial thermal therapy: a first line treatment for seizures due to hypothalamic hamartoma?

VX Du, SV Gandhi, HL Rekate, AD Mehta - Epilepsia, 2017 - Wiley Online Library
Successful treatment of hypothalamic hamartoma (HH) can result in the resolution of its
sequelae including epilepsy and rage attacks. Risks and morbidity of open surgical …

Subcentimeter epilepsy surgery targets by resting state functional magnetic resonance imaging can improve outcomes in hypothalamic hamartoma

VL Boerwinkle, ST Foldes, SJ Torrisi, H Temkit… - …, 2018 - Wiley Online Library
Objective The purpose of this study is to investigate the outcomes of epilepsy surgery
targeting the subcentimeter‐sized resting state functional magnetic resonance imaging (rs …

Magnetic resonance‐guided laser interstitial thermal therapy for drug‐resistant epilepsy: A systematic review and individual participant data meta‐analysis

JS Chen, AA Lamoureux, NA Shlobin, LM Elkaim… - …, 2023 - Wiley Online Library
Magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) has emerged as a
popular minimally invasive alternative to open resective surgery for drug‐resistant epilepsy …

Staged magnetic resonance-guided laser interstitial thermal therapy for hypothalamic hamartoma: analysis of ablation volumes and morphological considerations

N Gadgil, S Lam, IW Pan, M LoPresti, K Wagner… - …, 2020 - journals.lww.com
BACKGROUND Hypothalamic hamartomas (HH) are a challenging pathology that cause
gelastic seizures. Magnetic Resonance Imaging-guided Laser Interstitial Thermal Therapy …