Microfluidic reactors with immobilized enzymes—Characterization, dividing, perspectives

K Meller, M Szumski, B Buszewski - Sensors and actuators B: Chemical, 2017 - Elsevier
It is commonly known that enzymatic transformations are considerably more specific than
classical chemical reactions which usually lead to formation of byproducts. That is why the …

Increasing silicone mold longevity: A review of surface modification techniques for PDMS-PDMS double casting

A Ansari, R Trehan, C Watson, S Senyo - Soft materials, 2021 - Taylor & Francis
Polydimethylsiloxane (PDMS) has been used extensively for microfluidic devices due to its
chemical properties allowing for rapid molding and versatile biological application. Soft …

Photonic lab-on-a-chip: Integration of optical spectroscopy in microfluidic systems

I Rodríguez-Ruiz, TN Ackermann, X Muñoz-Berbel… - 2016 - ACS Publications
The integration of micro-optical elements with microfluidics leads to the highly promising
photonic lab-on-a-chip analytical systems (PhLoCs). In this work, we re-examine the main …

Fabrication of 3D microfluidic channels and in‐channel features using 3D printed, water‐soluble sacrificial mold

WH Goh, M Hashimoto - Macromolecular materials and …, 2018 - Wiley Online Library
Recent advent of additive manufacturing potentiates the fabrication of microchannels, albeit
with limitations in resolution of printed structures, freedom of geometry, and choice of …

Uric acid and creatinine biosensors with enhanced room-temperature storage stability by a multilayer enzyme matrix

Y Liu, X Luo, Y Dong, M Hui, L Xu, H Li, J Lv… - Analytica Chimica …, 2022 - Elsevier
Uric acid and creatinine are essential biomarkers for many diseases, such as gout,
hyperuricemia, kidney diseases and heart diseases. Electrochemical biosensors are …

Simple PDMS microdevice for biomedical applications

C Potrich, L Lunelli, M Cocuzza, SL Marasso, CF Pirri… - Talanta, 2019 - Elsevier
Polydimethylsiloxane (PDMS) is a well-known biocompatible polymer employed for many
applications in the biomedical field. In this study, the biocompatibility and versatility of PDMS …

Dual sacrificial molding: Fabricating 3D microchannels with overhang and helical features

WH Goh, M Hashimoto - Micromachines, 2018 - mdpi.com
Fused deposition modeling (FDM) has become an indispensable tool for 3D printing of
molds used for sacrificial molding to fabricate microfluidic devices. The freedom of design of …

Epithelial self-healing is recapitulated by a 3D biomimetic E-cadherin junction

DJ Cohen, M Gloerich… - Proceedings of the …, 2016 - National Acad Sciences
Epithelial monolayers undergo self-healing when wounded. During healing, cells
collectively migrate into the wound site, and the converging tissue fronts collide and form a …

New reusable solid biosensor with covalent immobilization of the horseradish peroxidase enzyme: in situ liberation studies of hydrogen peroxide by portable …

S Bocanegra-Rodríguez, N Jornet-Martínez… - ACS …, 2020 - ACS Publications
Herein, we reported a chemiluminescent biosensor based on the covalent immobilization of
the horseradish peroxidase (HRP) enzyme on a polydimethylsiloxane (PDMS) support to …

Direct Inscription of on-surface waveguides in polymers using a mid-ir fiber laser

JP Bérubé, C Frayssinous, J Lapointe, S Duval… - Optics …, 2019 - opg.optica.org
A detailed study of photo-inscribed optical waveguides in PMMA and polycarbonate using a
mid-IR laser is presented. The wavelength of the laser is tuned near the absorption peaks of …