Elevated C-reactive protein in the diagnosis, prognosis, and cause of cancer

KH Allin, BG Nordestgaard - Critical reviews in clinical laboratory …, 2011 - Taylor & Francis
The aim of this review is to summarize present evidence of an association between
circulating levels of C-reactive protein (CRP) and cancer risk, and to evaluate whether …

C-reactive protein: ligands, receptors and role in inflammation

L Marnell, C Mold, TW Du Clos - Clinical immunology, 2005 - Elsevier
C-reactive protein (CRP) is the prototypical acute phase serum protein, rising rapidly in
response to inflammation. CRP binds to phosphocholine (PC) and related molecules on …

Mendelian randomization: using genes as instruments for making causal inferences in epidemiology

DA Lawlor, RM Harbord, JAC Sterne… - Statistics in …, 2008 - Wiley Online Library
Observational epidemiological studies suffer from many potential biases, from confounding
and from reverse causation, and this limits their ability to robustly identify causal …

Genetically elevated C-reactive protein and ischemic vascular disease

J Zacho, A Tybjærg-Hansen, JS Jensen… - … England Journal of …, 2008 - Mass Medical Soc
Background Elevated levels of C-reactive protein (CRP) are associated with increased risks
of ischemic heart disease and ischemic cerebrovascular disease. We tested whether this is …

C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization

NJ Timpson, BG Nordestgaard, RM Harbord… - International journal of …, 2011 - nature.com
Objective: Using reciprocal Mendelian randomization, we aim to assess the direction of
causality in relationships between BMI and CRP and to demonstrate this as a promising …

The complex role of C-reactive protein in systemic lupus erythematosus

H Enocsson, J Karlsson, HY Li, Y Wu, I Kushner… - Journal of Clinical …, 2021 - mdpi.com
C-reactive protein (CRP) is well-known as a sensitive albeit unspecific biomarker of
inflammation. In most rheumatic conditions, the level of this evolutionarily highly conserved …

C-reactive protein is a mediator of cardiovascular disease

RJ Bisoendial, SM Boekholdt, M Vergeer… - European heart …, 2010 - academic.oup.com
C-reactive protein is postulated to embody an index that can reflect cardiovascular risk and
can be used to independently predict major cardiovascular events and mortality. On the …

Genetic variation, C-reactive protein levels, and incidence of diabetes

A Dehghan, I Kardys, MPM de Maat, AG Uitterlinden… - …, 2007 - Am Diabetes Assoc
C-reactive protein (CRP) has been shown to be associated with type 2 diabetes, but whether
CRP has a causal role is not yet clear. We examined the association in the Rotterdam Study …

C-reactive protein in rheumatology: biology and genetics

B Rhodes, BG Fürnrohr, TJ Vyse - Nature Reviews Rheumatology, 2011 - nature.com
Measurement of serum C-reactive protein (CRP) level is in widespread clinical use as a
sensitive marker of inflammation. CRP has a role in the clearance of bacteria and of dying …

C-reactive protein gene polymorphisms, C-reactive protein blood levels, and cardiovascular disease risk

FG Hage, AJ Szalai - Journal of the American college of cardiology, 2007 - jacc.org
C-reactive protein (CRP), a blood marker of inflammation and a hallmark of the acute-phase
response, has been shown to be a powerful and specific predictor of cardiovascular event …