Zebrafish models of neurodevelopmental disorders: limitations and benefits of current tools and techniques

R Vaz, W Hofmeister, A Lindstrand - International journal of molecular …, 2019 - mdpi.com
For the past few years there has been an exponential increase in the use of animal models
to confirm the pathogenicity of candidate disease-causing genetic variants found in patients …

Zebrafish as a systems toxicology model for developmental neurotoxicity testing

Y Nishimura, S Murakami, Y Ashikawa… - Congenital …, 2015 - Wiley Online Library
The developing brain is extremely sensitive to many chemicals. Exposure to neurotoxicants
during development has been implicated in various neuropsychiatric and neurological …

Internal state dynamics shape brainwide activity and foraging behaviour

JC Marques, M Li, D Schaak, DN Robson, JM Li - Nature, 2020 - nature.com
The brain has persistent internal states that can modulate every aspect of an animal's mental
experience,,–. In complex tasks such as foraging, the internal state is dynamic …

Unpredictable chronic stress model in zebrafish (Danio rerio): behavioral and physiological responses

ÂL Piato, KM Capiotti, AR Tamborski, JP Oses… - Progress in Neuro …, 2011 - Elsevier
Zebrafish (Danio rerio) have emerged as a promising model organism to study
development, toxicology, pharmacology, and neuroscience, among other areas. Despite the …

Molecular psychiatry of zebrafish

AM Stewart, JFP Ullmann, WHJ Norton, MO Parker… - Molecular …, 2015 - nature.com
Due to their well-characterized neural development and high genetic homology to
mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field …

Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems

TL Tay, O Ronneberger, S Ryu, R Nitschke… - Nature …, 2011 - nature.com
Essential components of animal behaviour are modulated by dopaminergic (DA) and
noradrenergic circuitry. In this study, we reveal at cellular resolution the complete set of …

[HTML][HTML] Carbamazepine, venlafaxine, tramadol, and their main metabolites: Toxicological effects on zebrafish embryos and larvae

P Rodrigues, L Guimarães, AP Carvalho… - Journal of Hazardous …, 2023 - Elsevier
Pharmaceutical compounds and their metabolites are found in natural and wastewater.
However, investigation of their toxic effects on aquatic animals has been neglected …

Zebrafish neurobehavioral phenomics for aquatic neuropharmacology and toxicology research

AV Kalueff, DJ Echevarria, S Homechaudhuri… - Aquatic Toxicology, 2016 - Elsevier
Zebrafish (Danio rerio) are rapidly emerging as an important model organism for aquatic
neuropharmacology and toxicology research. The behavioral/phenotypic complexity of …

Zebrafish in endocrine systems: recent advances and implications for human disease

H Löhr, M Hammerschmidt - Annual review of physiology, 2011 - annualreviews.org
Since its introduction as a genetic vertebrate model system approximately 30 years ago, the
focus of zebrafish research has increasingly shifted to questions that are also relevant for …

Molecular neuroanatomy and chemoarchitecture of the neurosecretory preoptic‐hypothalamic area in zebrafish larvae

U Herget, A Wolf, MF Wullimann… - Journal of Comparative …, 2014 - Wiley Online Library
The paraventricular nucleus (PVN) in mammals is the main hypothalamic nucleus
controlling hormone release in the pituitary and plays pivotal roles in homeostasis. While the …