[HTML][HTML] Epstein–Barr virus and genetic risk variants as determinants of T-bet+ B cell-driven autoimmune diseases

L Bogers, KL Kuiper, J Smolders, J Rip, MM van Luijn - Immunology letters, 2023 - Elsevier
B cells expressing the transcription factor T-bet are found to have a protective role in viral
infections, but are also considered major players in the onset of different types of …

Function and Regulation of Age‐Associated B Cells in Diseases

Z Geng, Y Cao, L Zhao, L Wang… - Journal of Cellular …, 2025 - Wiley Online Library
The aging process often leads to immune‐related diseases, including infections, tumors,
and autoimmune disorders. Recently, researchers identified a special subpopulation of B …

Combination of proviral and antiviral roles of B cell-intrinsic STAT1 expression defines parameters of chronic gammaherpesvirus infection

ER Johansen, DL Schmalzriedt, D Avila, PA Sylvester… - Mbio, 2024 - journals.asm.org
Gammaherpesviruses are species-specific, ubiquitous pathogens that establish lifelong
infection in their hosts and are associated with cancers, including B cell lymphomas. Type I …

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles

R Krause, P Ogongo, L Tezera, M Ahmed… - Communications …, 2024 - nature.com
B cells are important in tuberculosis (TB) immunity, but their role in the human lung is
understudied. Here, we characterize B cells from lung tissue and matched blood of patients …

[HTML][HTML] Impact of Epstein–Barr Virus Nuclear Antigen 1 on Neuroinflammation in PARK2 Knockout Mice

D Cossu, Y Tomizawa, S Noda, E Momotani… - International Journal of …, 2024 - mdpi.com
This study aimed to explore the intricate relationship between mitochondrial dysfunction,
infection, and neuroinflammation, focusing specifically on the impact of pathogenic epitopes …

B cell-intrinsic IFN-γ promotes excessive CD11c+ age-associated B cell differentiation and compromised germinal center selection in lupus mice

S Liu, W Zhang, S Tian, Y Zhang, Z Yin, G Huang… - Cellular …, 2024 - Elsevier
CD11c+ age-associated B cells (ABCs) have emerged as a key component in protective and
autoreactive B cell responses. Lupus is an autoimmune disorder linked to reduced efficacy …

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and putative functional roles

R Krause, P Ogongo, L Tezera, M Ahmed, I Mbano… - 2023 - researchsquare.com
B cells are important in tuberculosis (TB) immunity, but their role in the human lung is
understudied. Here, we characterize B cells from lung tissue and matched blood of TB …

[PDF][PDF] Impact of Epstein-Barr Virus Nuclear Antigen 1 on Neuroinflammation in PARK2 Knockout Mice with Mitochondrial Dysfunction

D Cossu, Y Tomizawa, S Noda, E Momotani… - 2024 - preprints.org
This study aimed to explore the intricate relationship between mitochondrial dysfunction,
infections, and neuroinflammation, focusing specifically on the impact of pathogenic …

Vaccination against gammaherpesvirus attenuates viral enhanced disease in a murine model of multiple sclerosis

AR Rosen - 2024 - open.library.ubc.ca
Multiple Sclerosis (MS) is a chronic, neurodegenerative autoimmune disease of the central
nervous system (CNS). The aetiology of the disease remains unknown; however, it is …

[PDF][PDF] B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles

M Chambers, A Ngoepe, M Magnoumba, D Muema… - scienceopen.com
B cells are important in tuberculosis (TB) immunity, but their role in the human lung is
understudied. Here, we characterize B cells from lung tissue and matched blood of patients …