A review on curability of cancers: more efforts for novel therapeutic options are needed

S Wang, Y Liu, Y Feng, J Zhang, J Swinnen, Y Li, Y Ni - Cancers, 2019 - mdpi.com
Cancer remains a major cause of death globally. Given its relapsing and fatal features,
curing cancer seems to be something hardly possible for the majority of patients. In view of …

An introduction to the clinical practice of theranostics in oncology

JH Turner - The British journal of radiology, 2018 - academic.oup.com
“Those who cannot remember the past are condemned to repeat it.” George Santayana
1905 “If men could learn from history, what lessons it might teach us! But passion and party …

Association between radioactive iodine treatment for pediatric and young adulthood differentiated thyroid cancer and risk of second primary malignancies

E Pasqual, S Schonfeld, LM Morton… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Since the 1980s, both the incidence of differentiated thyroid cancer (DTC) and
use of radioactive iodine (RAI) treatment increased markedly. RAI has been associated with …

Association of radioactive iodine treatment with cancer mortality in patients with hyperthyroidism

CM Kitahara, AB De Gonzalez, A Bouville… - JAMA internal …, 2019 - jamanetwork.com
Importance Radioactive iodine (RAI) has been used extensively to treat hyperthyroidism
since the 1940s. Although widely considered a safe and effective therapy, RAI has been …

SWI/SNF complex mutations promote thyroid tumor progression and insensitivity to redifferentiation therapies

M Saqcena, LJ Leandro-Garcia, JLV Maag… - Cancer Discovery, 2021 - AACR
Mutations of subunits of the SWI/SNF chromatin remodeling complexes occur commonly in
cancers of different lineages, including advanced thyroid cancers. Here we show that thyroid …

[PDF][PDF] Normal-tissue tolerance to radiopharmaceutical therapies, the knowns and the unknowns

RL Wahl, G Sgouros, A Iravani, H Jacene… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Radiopharmaceutical therapies are gaining increasing prominence as they improve survival
in patients with common diseases such as metastatic prostate cancer (1, 2). However …

Genomic and transcriptomic characteristics of metastatic thyroid cancers with exceptional responses to radioactive iodine therapy

L Boucai, M Saqcena, F Kuo, RK Grewal, N Socci… - Clinical Cancer …, 2023 - AACR
Purpose: The determinants of response or resistance to radioiodine (RAI) are unknown. We
aimed to identify genomic and transcriptomic factors associated with structural responses to …

Cancer risk after radioactive iodine treatment for hyperthyroidism: a systematic review and meta-analysis

SR Shim, CM Kitahara, ES Cha, SJ Kim… - JAMA Network …, 2021 - jamanetwork.com
Importance Whether radioactive iodine (RAI) therapy for hyperthyroidism can increase
cancer risk remains a controversial issue in medicine and public health. Objectives To …

Linear association between radioactive iodine dose and second primary malignancy risk in thyroid cancer

KJ Kim, KJ Kim, J Choi, NH Kim… - JNCI: Journal of the …, 2023 - academic.oup.com
Background We aimed to investigate whether the risk of second primary malignancy (SPM)
in patients with thyroid cancer (TC) receiving radioactive iodine (RAI) therapy rises in a …

A systematic review and meta-analysis of subsequent malignant neoplasm risk after radioactive iodine treatment of thyroid cancer

CY Yu, O Saeed, AS Goldberg, S Farooq, R Fazelzad… - Thyroid, 2018 - liebertpub.com
Background: The potential risk of subsequent malignant neoplasms (SMNs) after radioactive
iodine (RAI) treatment of thyroid cancer (TC) is an important concern. Methods: A systematic …