The thalamus, with its cortical, subcortical, and cerebellar connections, is a critical node in
networks supporting cognitive functions known to decline in normal aging, including …

Age-related increase in frailty is accompanied by a fundamental shift in cellular iron
homeostasis. By promoting oxidative stress, the intracellular accumulation of non-heme iron …

The individual alpha peak frequency (IAPF) of the human electroencephalography (EEG)
typically experiences slowing with increasing age. Despite this hallmark change, studies that …

One objective of modern neuroimaging is to identify markers that can aid in diagnosis,
disease progression monitoring and long-term drug impact analysis. In this study, Parkinson …

As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination and …

Normal ageing is associated with characteristic changes in brain microstructure. Although in
vivo neuroimaging captures spatial and temporal patterns of age-related changes of …

The aim of this large‐sample cross‐sectional voxel‐based morphometry (VBM) study of
anatomical brain data was to investigate linear and nonlinear age‐related trajectories of …

Quantitative susceptibility mapping (QSM) measures bulk susceptibilities in the brain, which
can arise from many sources. In iron-rich subcortical gray matter (GM), non-heme iron is a …

Background Microstructural changes in deep gray matter (DGM) nuclei are related to
physiological behavior, cognition, and memory. Therefore, it is critical to study age …

Despite the constant improvement of algorithms for automated brain tissue classification, the
accurate delineation of subcortical structures using magnetic resonance images (MRI) data …