Tuberculosis treatment monitoring and outcome measures: new interest and new strategies
J Heyckendorf, SB Georghiou, N Frahm… - Clinical microbiology …, 2022 - Am Soc Microbiol
Despite the advent of new diagnostics, drugs and regimens, tuberculosis (TB) remains a
global public health threat. A significant challenge for TB control efforts has been the …
global public health threat. A significant challenge for TB control efforts has been the …
Does Mycobacterium tuberculosis var. bovis Survival in the Environment Confound Bovine Tuberculosis Control and Eradication? A Literature Review
Bovine tuberculosis (bTB) is one of the globe's most common, multihost zoonoses and
results in substantial socioeconomic costs for governments, farming industries, and tax …
results in substantial socioeconomic costs for governments, farming industries, and tax …
High Mycobacterium tuberculosis bacillary loads detected by tuberculosis molecular bacterial load assay in patient stool: a potential alternative for nonsputum …
E Musisi, A Sessolo, S Kaswabuli… - Microbiology …, 2022 - Am Soc Microbiol
Not all patients produce sputum, yet most available TB tests use sputum. We investigated
the utility of a novel RNA-based quantitative test, the tuberculosis molecular bacterial load …
the utility of a novel RNA-based quantitative test, the tuberculosis molecular bacterial load …
Heat Inactivation Renders Sputum Safe and Preserves Mycobacterium tuberculosis RNA for Downstream Molecular Tests
W Sabiiti, K Azam, E Esmeraldo, N Bhatt… - Journal of clinical …, 2019 - Am Soc Microbiol
ABSTRACT The World Health Organization End Tuberculosis (TB) strategy has called for
the development of—and increased access to—effective tools for diagnosis and treatment of …
the development of—and increased access to—effective tools for diagnosis and treatment of …
Mycobactericidal effects of different regimens measured by molecular bacterial load assay among people treated for multidrug-resistant tuberculosis in Tanzania
Rifampin or multidrug-resistant tuberculosis (RR/MDR-TB) treatment has largely transitioned
to regimens free of the injectable aminoglycoside component, despite the drug class' …
to regimens free of the injectable aminoglycoside component, despite the drug class' …
A tuberculosis molecular bacterial load assay (TB-MBLA)
Tuberculosis is caused by Mycobacterium tuberculosis (Mtb), a pathogen classified by the
United Nations (UN) as a dangerous category B biological substance. For the sake of the …
United Nations (UN) as a dangerous category B biological substance. For the sake of the …
Tuberculosis Molecular Bacterial Load Assay reveals early delayed bacterial killing in patients with relapse
Bacterial killing in patients with tuberculosis (TB) relapse was compared to that in patients
achieving cure, measured by TB molecular bacterial load assay (TB-MBLA) or mycobacteria …
achieving cure, measured by TB molecular bacterial load assay (TB-MBLA) or mycobacteria …
Systematic assessment of clinical and bacteriological markers for tuberculosis reveals discordance and inaccuracy of symptom-based diagnosis for treatment …
Background Clinical symptoms are the benchmark of tuberculosis (TB) diagnosis and
monitoring of treatment response but are not clear how they relate to TB bacteriology …
monitoring of treatment response but are not clear how they relate to TB bacteriology …
[HTML][HTML] A practical approach to render tuberculosis samples safe for application of tuberculosis molecular bacterial load assay in clinical settings without a biosafety …
Background Mycobacterium tuberculosis is a category B infectious pathogen requiring level-
3-containment laboratories for handling. We assessed the efficacy of heat and Guanidine …
3-containment laboratories for handling. We assessed the efficacy of heat and Guanidine …
OMNIgene. SPUTUM suppresses contaminants while maintaining Mycobacterium tuberculosis viability and obviates cold-chain transport
K Azam, N Cadir, C Madeira, SH Gillespie… - ERJ open …, 2018 - Eur Respiratory Soc
Tuberculosis (TB) diagnostics are centralised, requiring long-distance transportation of
specimens in most resource-limited settings. We evaluated the ability of OMNIgene …
specimens in most resource-limited settings. We evaluated the ability of OMNIgene …