Gene expression in cells is determined by the epigenetic state of chromatin. Therefore, the
study of epigenetic changes is very important to understand the regulatory mechanism of …

Bull fertility is an important economic trait in sustainable cattle production, as infertile or
subfertile bulls give rise to large economic losses. Current methods to assess bull fertility are …

Background Characterization of the molecular mechanisms underlying hair follicle
development is of paramount importance in the genetic improvement of wool-related traits in …

Background Conflicting results regarding alterations to sperm DNA methylation in cases of
spermatogenesis defects, male infertility and poor developmental outcomes have been …

Background Cytosine DNA methylation is a heritable epigenetic mark present in most
eukaryotic groups. While the patterns and functions of DNA methylation have been …

Advanced paternal age is associated with increased risks for reproductive and offspring
medical problems. Accumulating evidence suggests age-related changes in the sperm …

The epigenome is dynamic and forged by epigenetic mechanisms, such as DNA
methylation, histone modifications, chromatin remodeling, and non-coding RNA species …

Background The functional annotation of genomes, including chromatin accessibility and
modifications, is important for understanding and effectively utilizing the increased amount of …

Background Insights into the genetic basis of complex traits and disease in both human and
livestock species have been achieved over the past decade through detection of genetic …

Background Efforts to improve animal health, and understand genetic bases for production,
may benefit from a comprehensive analysis of animal genomes and epigenomes. Although …