ABSTRACT SQSTM1 (also known as p62) is a multifunctional stress-inducible scaffold
protein involved in diverse cellular processes. Its functions are tightly regulated through an …

p62 is a stress‐inducible protein able to change among binding partners, cellular
localizations and form liquid droplet structures in a context‐dependent manner. This protein …

CTLA-4 immune checkpoint blockade is clinically effective in a subset of patients with
metastatic melanoma. We identify a subcluster of MAGE-A cancer-germline antigens …

Background Autophagy is a cellular pathway that regulates transportation of cytoplasmic
macromolecules and organelles to lysosomes for degradation. Autophagy is involved in …

Cholangiocarcinoma (CCA) is a malignant tumor that originates from the biliary epithelial
cells. It is characterized by a difficult diagnosis and limited treatment options. Autophagy is a …

p62/SQSTM 1 is a multifunctional signaling hub and autophagy adaptor with many binding
partners, which allow it to activate mTORC 1‐dependent nutrient sensing, NF‐κB‐mediated …

Abstract Sequestosome 1 (SQSTM1)/p62 is an adapter protein mainly involved in the
transportation, degradation and destruction of various proteins that cooperates with …

Autophagy-related long-chain noncoding ribonucleic acids play a vital role in the
development of esophageal adenocarcinoma. This study aimed to construct a prognostic …

Esophageal cancers (EC) are highly aggressive tumors, commonly presented in a locally
advanced stage with a poor prognosis and survival. Up to 50% of the patients are eligible for …

Autophagy is a lysosomal degradation and recycling process implicated in cancer
progression and therapy resistance. We assessed the impact of basal autophagy in colon …