Next-generation microbiology: from comparative genomics to gene function
Microbiology is at a turning point in its 120-year history. Widespread next-generation
sequencing has revealed genetic complexity among bacteria that could hardly have been …
sequencing has revealed genetic complexity among bacteria that could hardly have been …
The largely unexplored biology of small proteins in pro‐and eukaryotes
R Steinberg, HG Koch - The FEBS journal, 2021 - Wiley Online Library
The large abundance of small open reading frames (smORFs) in prokaryotic and eukaryotic
genomes and the plethora of smORF‐encoded small proteins became only apparent with …
genomes and the plethora of smORF‐encoded small proteins became only apparent with …
Extensive remodelling of the cell wall during the development of Staphylococcus aureus bacteraemia
The bloodstream represents a hostile environment that bacteria must overcome to cause
bacteraemia. To understand how the major human pathogen Staphylococcus aureus …
bacteraemia. To understand how the major human pathogen Staphylococcus aureus …
Polyether Ionophore antibiotics target drug-resistant clinical isolates, Persister cells, and biofilms
M Wollesen, K Mikkelsen, MS Tvilum… - Microbiology …, 2023 - Am Soc Microbiol
Polyether ionophores are complex natural products known to transport various cations
across biological membranes. While several members of this family are used in agriculture …
across biological membranes. While several members of this family are used in agriculture …
Lipoteichoic acid biosynthesis by Staphylococcus aureus is controlled by the MspA protein
Staphylococcus aureus produces a plethora of virulence factors critical to its ability to
establish an infection and cause disease. We have previously characterized a small …
establish an infection and cause disease. We have previously characterized a small …
The MpsB protein contributes to both the toxicity and immune evasion capacity of Staphylococcus aureus
Understanding the role specific bacterial factors play in the development of severe disease
in humans is critical if new approaches to tackle such infections are to be developed. In this …
in humans is critical if new approaches to tackle such infections are to be developed. In this …
The Old Yellow Enzyme OfrA Fosters Staphylococcus aureus Survival via Affecting Thiol-Dependent Redox Homeostasis
ES Ibrahim, K Ohlsen - Frontiers in Microbiology, 2022 - frontiersin.org
Old yellow enzymes (OYEs) are widely found in the bacterial, fungal, and plant kingdoms but
absent in humans and have been used as biocatalysts for decades. However, OYEs' …
absent in humans and have been used as biocatalysts for decades. However, OYEs' …
[图书][B] The Small Protein ScrA Is a Novel Regulator of Staphylococcus aureus Virulence Acting as an Intermediary Between the ArlRS and SaeRS Two-Component …
MA Wittekind - 2023 - search.proquest.com
Staphylococcus aureus is a Gram-positive opportunistic pathogen capable of causing life
threatening infections. A series of regulators controls expression of an array of virulence …
threatening infections. A series of regulators controls expression of an array of virulence …
Lipoteichoic acid biosynthesis by Staphylococcus aureus is controlled by the MspA protein through competitive interference
Staphylococcus aureus produces a plethora of virulence factors critical to its ability to
establish an infection and cause disease. We have previously characterised a small …
establish an infection and cause disease. We have previously characterised a small …
[PDF][PDF] Characterisation of a membrane protein, MspA, that is critical for Staphylococcus aureus pathogenesis
AA Alnahari, R Massey - 2023 - research-information.bris.ac.uk
Staphylococcus aureus is one of the most common human pathogenic bacteria. It can cause
various infections, ranging from superficial skin infections to sepsis and other life-threatening …
various infections, ranging from superficial skin infections to sepsis and other life-threatening …