N Bazargani, D Attwell - Nature neuroscience, 2016 - nature.com
The discovery that transient elevations of calcium concentration occur in astrocytes, and release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
Dopamine is involved in physiological processes like learning and memory, motor control and reward, and pathological conditions such as Parkinson's disease and addiction. In …
The identification of the presence of active signaling between astrocytes and neurons in a process termed gliotransmission has caused a paradigm shift in our thinking about brain …
J Wahis, A Baudon, F Althammer, D Kerspern… - Nature …, 2021 - nature.com
Oxytocin (OT) orchestrates social and emotional behaviors through modulation of neural circuits. In the central amygdala, the release of OT modulates inhibitory circuits and, thereby …
Astrocytes, a major type of glial cell, are known to play key supportive roles in brain function, contributing to ion and neurotransmitter homeostasis, maintaining the blood–brain barrier …
RA Cunha - Journal of neurochemistry, 2016 - Wiley Online Library
The adenosine modulation system mostly operates through inhibitory A1 (A1R) and facilitatory A2A receptors (A2AR) in the brain. The activity‐dependent release of adenosine …
The amygdala plays key roles in fear and anxiety. Studies of the amygdala have largely focused on neuronal function and connectivity. Astrocytes functionally interact with neurons …
A Covelo, A Araque - elife, 2018 - elifesciences.org
Accumulating evidence indicates that astrocytes are actively involved in brain function by regulating synaptic activity and plasticity. Different gliotransmitters, such as glutamate, ATP …
The term 'tripartite synapse'refers to a concept in synaptic physiology based on the demonstration of the existence of bidirectional communication between astrocytes and …