State-of-the-art tissue-clearing methods provide subcellular-level optical access to intact
tissues from individual organs and even to some entire mammals. When combined with light …

Since the first place cell was recorded and the cognitive-map theory was subsequently
formulated, investigation of spatial representation in the hippocampal formation has evolved …

To guide navigation, the nervous system integrates multisensory self-motion and landmark
information. We dissected how these inputs generate spatial representations by recording …

The septo–hippocampal pathway adjusts CA1 network excitability to different behavioral
states and is crucially involved in theta rhythmogenesis. In the medial septum, cholinergic …

The hippocampal formation is critically involved in learning and memory and contains a
large proportion of neurons encoding aspects of the organism's spatial surroundings. In the …

Locomotor speed is a basic input used to calculate one's position, but where this signal
comes from is unclear. We identified neurons in the supramammillary nucleus (SuM) of the …

Abstract The theta oscillation (5–10 Hz) is a prominent behavior-specific brain rhythm. This
review summarizes studies showing the multifaceted role of theta rhythm in cognitive …

Hippocampal theta oscillations coordinate neuronal firing to support memory and spatial
navigation. The medial septum (MS) is critical in theta generation by two possible …

INTRODUCTION Associative learning is essential for survival, and the mammalian
hippocampal neurocircuitry has been shown to play a central role in the formation of specific …

Locomotion activates an array of sensory inputs that may help build the self-position map of
the medial entorhinal cortex (MEC). In this map, speed-coding neurons are thought to …