Despite aging being by far the greatest risk factor for highly prevalent neurodegenerative
disorders, the molecular underpinnings of age-related brain changes are still not well …

Treatment of the neuronal ceroid lipofuscinoses, also known as Batten disease, is at the start
of a new era because of diagnostic and therapeutic advances relevant to this group of …

The neuronal ceroid lipofuscinoses comprise a group of neurodegenerative lysosomal
storage disorders caused by mutations in at least 13 different genes and primarily affect the …

The neuronal ceroid lipofuscinoses (NCLs) are a group of inherited neurodegenerative
disorders that affect children and adults. They share some similar clinical features and the …

Abstract Neuronal Ceroid Lipofuscinoses (NCLs), commonly known as Batten disease,
constitute a group of the most prevalent neurodegenerative lysosomal storage disorders …

The neuronal ceroid lipofuscinoses (NCL) are a group of disorders defined by shared
clinical and pathological features, including seizures and progressive decline in vision …

Neuronal ceroid lipofuscinoses (NCLs) are a group of rare, inherited, neurodegenerative
lysosomal storage disorders that affect children and adults. They are traditionally grouped …

Kufs disease is the major adult form of neuronal ceroid lipofuscinosis, but is rare and difficult
to diagnose. Diagnosis was traditionally dependent on the demonstration of characteristic …

Heat shock proteins (HSPs) are a family of molecular chaperones that regulate essential
protein refolding and triage decisions to maintain protein homeostasis. Numerous co …

Mitochondrial complex V (ATP synthase) is a remarkable molecular motor crucial in
generating ATP and sustaining mitochondrial function. Its importance in cellular metabolism …