Traditional Chinese medicine (TCM) is a holistic approach to health that attempts to bring
the body, mind and spirit into harmony. Entering 21st century, TCM is getting more and more …

Metabolomics represent a global understanding of metabolite complement of integrated
living systems and dynamic responses to the changes of both endogenous and exogenous …

Natural products historically have been a rich source of lead molecules in drug discovery,
based on their capability to create unique and diverse chemical structures. However, it is …

Protein function can be regulated via post-translational modifications by numerous
enzymatic and non-enzymatic mechanisms, including oxidation of cysteine and methionine …

Compounds that delay aging might also postpone age-related diseases and extend
healthspan in humans. Icariin is a flavonol extracted from several plant species of the …

Abstract Traditional Chinese herb medicines (TCHMs) have been used in the treatment of a
variety of diseases for thousands of years in Asian countries. The active components of …

The aim of the study was to investigate the effect of icariin (ICA) on cardiac aging through its
effects on the SIRT6 enzyme and on the NF‐κB pathway. Investigating the effect of ICA on …

Inflammation is an important component of normal responses to infection and injury.
However, chronic activation of the immune system, perhaps due to aberrant responses to …

Obesity and obesity‐related complications are on the increase both in the developed and
developing world. Since existing pharmaceuticals fail to come up with long‐term solutions to …

Ethnopharmacological relevance Aging is related to many factors, such as genes, oxidative
damage, metabolic abnormalities, immune regulation and sex hormones. This article …