Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Extracellular vesicles (EVs) have increasingly been recognized as important cell surrogates
influencing many pathophysiological processes, including cellular homeostasis, cancer …

Graft-versus-host disease (GVHD)–associated dry eye disease is characterized by extensive
inflammatory destruction in the ocular surface and causes unbearable pain and visual …

We have demonstrated, for the first time that microvesicles, a sub-type of extracellular
vesicles (EVs) derived from hCMEC/D3: a human brain endothelial cell (BEC) line transfer …

Corneal epithelial defects and excessive wound healing might lead to severe complications.
As stem cells can self-renew infinitely, they are a promising solution for regenerating the …

Due to the prevalence of individuals suffering from chronic wounds, developing safe and
effective wound care agents are one of the more prominent fields of research in biology …

The therapeutic effects of secreted factors (secretome) produced by bone marrow-derived
human mesenchymal stem cells (MSCs) were evaluated as a function of their growth in 2D …

Intrinsic shortcomings associated with conventional therapeutic strategies often compromise
treatment efficacy in clinical ophthalmology, prompting the rapid development of versatile …

Due to their robust immunomodulatory capabilities, mesenchymal stem/stromal cells (MSCs)
have been used as a cellular therapy for a number of human diseases. Part of the …

Retinal degeneration (RD) is one of the dominant causes of irreversible vision impairment
and blindness worldwide. However, the current effective therapeutics for RD in the …