Preimplantation genetic diagnosis (PGD) was introduced at the beginning of the 1990s as
an alternative to prenatal diagnosis, to prevent termination of pregnancy in couples with a …

Today, preimplantation genetic diagnosis (PGD) is offered in over 40 centres worldwide for
an expanded range of genetic defects causing disease. This very early form of prenatal …

The first edition of the Textbook of Assisted Reproductive Techniques was published in
2001. As the textbook now enters its sixth edition, some 45 years since the birth of Louise …

Preimplantation genetic diagnosis (PGD) of single gene disorders relies on PCR‐based
tests performed on single cells (polar bodies or blastomeres). Despite the use of …

We have applied a new method of genetic analysis, called 'minisequencing', to
preimplantation genetic diagnosis (PGD) of monogenic disorders from single cells. This …

PGD is a well accepted reproductive choice for couples at genetic risk and involves the
diagnosis and transfer of unaffected IVF embryos. PGD for monogenetic diseases is most …

There is increasing interest in the use of preimplantation genetic diagnosis (PGD) as an
alternative to routine prenatal diagnosis. However, the costs associated with development …

The first clinically applied preimplantation genetic diagnosis (PGD) was reported more than
a decade ago and since then PGD has known an exponential growth. This first report …

Preimplantation genetic diagnosis (PGD) is usually performed on cleavage stage embryos
on day 3 post‐insemination. Fluorescent in situ hybridization (FISH) has revealed four …

Materials and Methods Essentially there are two laboratory components involved in PGD.
The first involves the collection of diagnostic material for testing. This is usually performed in …