Following the impressive progress in the treatment of relapsing–remitting multiple sclerosis
(MS), the major challenge ahead is the development of treatments to prevent or delay the …

Neuroinflammation is a significant contributor to Alzheimer's disease (AD). Until now, PET
imaging of the translocator protein (TSPO) has been widely used to depict the neuroimmune …

Background Choroid plexuses (CPs) have been suggested as a key gateway for
inflammation in experimental autoimmune encephalitis, but in vivo evidence of their …

Objective To determine the prognostic value of persisting neuroinflammation in multiple
sclerosis (MS) lesions, we developed a 18 kDa‐translocator‐protein‐positron emission …

Introduction Increasing evidence suggests that neuroinflammation is active in Parkinson
disease (PD) and contributes to neurodegeneration. This process can be studied in vivo with …

Background and Objectives Recent imaging studies have suggested a possible involvement
of the choroid plexus (CP) in multiple sclerosis (MS). Here, we investigated whether CP …

Mouse models of Alzheimer's disease (AD) are valuable but do not fully recapitulate human
AD pathology, such as spontaneous Tau fibril accumulation and neuronal loss …

The integration of transcriptomic and neuroimaging data," imaging transcriptomics," has
recently emerged to generate hypotheses about potential biological pathways underlying …

Objectives To explore in vivo innate immune cell activation as a function of the distance from
ventricular CSF in patients with multiple sclerosis (MS) using [18F]-DPA714 PET and to …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of
people worldwide. Positron emission tomography/magnetic resonance (PET/MR) imaging is …