The global pandemic of SARS-CoV-2, the causative viral pathogen of COVID-19, has driven
the biomedical community to action—to uncover and develop antiviral interventions. One …

Coronaviruses, named for their crown-like spiked surface, are genetically diverse and can
infect multiple animal species, including bats, pigs, cats, rodents, and humans. Aside from …

The COVID-19 pandemic has highlighted the need to quickly and reliably prioritize clinically
approved compounds for their potential effectiveness for severe acute respiratory syndrome …

Abstract Machine learning (ML) outperforms traditional approaches in many molecular
design tasks. ML models usually predict molecular properties from a 2D chemical graph or a …

The uncontrolled spread of the COVID-19 pandemic caused by the new coronavirus SARS-
CoV-2 during 2020–2021 is one of the most devastating events in the history, with …

Compound repurposing is an important strategy for the identification of effective treatment
options against SARS-CoV-2 infection and COVID-19 disease. In this regard, SARS-CoV-2 …

While vaccine development will hopefully quell the global pandemic of COVID-19 caused by
SARS-CoV-2, small molecule drugs that can effectively control SARS-CoV-2 infection are …

Drug repurposing is a rapid approach to identify therapeutics for the treatment of emerging
infectious diseases such as COVID-19. To address the urgent need for treatment options, we …

Understanding the SARS-CoV-2 virus' pathways of infection, virus–host–protein interactions,
and mechanisms of virus-induced cytopathic effects will greatly aid in the discovery and …

Objective Reports that the over-the-counter histamine H 2 receptor antagonist famotidine
could help treat the novel coronavirus disease (COVID-19) appeared from April 2020. We …