Allogeneic haematopoietic stem cell transplantation (allo-HSCT) was the first successful
therapy for patients with haematological malignancies, predominantly owing to graft-versus …

Allogeneic stem cell transplantation (allo-SCT) is a curable method for the treatment of
hematological malignancies. In the past two decades, the establishment of haploidentical …

There is considerable interest in therapeutic transfer of regulatory T cells (Tregs) for
controlling aberrant immune responses. Initial clinical trials have shown the safety of Tregs …

Abstract Human CD4+ 25− T cells cultured in interleukin 2 (IL-2), rapamycin, and
transforming growth factor β (TGFβ) along with anti-CD3 monoclonal antibody–loaded …

Allogeneic haematopoietic stem cell transplantation (HCT) is a potent immunotherapy with
curative potential for several haematological disorders. Overcoming the immunological …

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative therapy for
many types of cancer. Genetic disparities between donor and host can result in immune …

Graft-versus-host disease (GVHD), manifesting as either acute (aGVHD) or chronic
(cGVHD), presents significant life-threatening complications following allogeneic …

Macrophages (MΦs) are an important immune cell population that are essential for tissue
homeostasis and disease pathogenesis. MΦs are now classified as either M1, which …

Simple Summary Adoptive immunotherapy has emerged as an effective alternative of
mounting impact to the current standard of care in cancer, viral infections, and recently …

Biological sex affects immunity broadly with recognized effects on incidence and severity of
autoimmune diseases, infections and malignancies. Consequences of sex on alloimmunity …