Natural products as anticancer agents: current status and future perspectives

A Naeem, P Hu, M Yang, J Zhang, Y Liu, W Zhu… - Molecules, 2022 - mdpi.com
Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

[HTML][HTML] Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence

R Kotecha, A Takami, JL Espinoza - Oncotarget, 2016 - ncbi.nlm.nih.gov
Cancer chemoprevention involves the use of different natural or biologic agents to inhibit or
reverse tumor growth. Epidemiological and pre-clinical data suggest that various natural …

Targeting arachidonic acid pathway by natural products for cancer prevention and therapy

NS Yarla, A Bishayee, G Sethi, P Reddanna… - Seminars in cancer …, 2016 - Elsevier
Arachidonic acid (AA) pathway, a metabolic process, plays a key role in carcinogenesis.
Hence, AA pathway metabolic enzymes phospholipase A 2 s (PLA 2 s), cyclooxygenases …

[HTML][HTML] Activation of Nrf2 signaling by natural products-can it alleviate diabetes?

M Matzinger, K Fischhuber, EH Heiss - Biotechnology advances, 2018 - Elsevier
Type 2 diabetes mellitus (DM) has reached pandemic proportions and effective prevention
strategies are wanted. Its onset is accompanied by cellular distress, the nuclear factor …

Cruciferous vegetables, isothiocyanates, and bladder cancer prevention

B Abbaoui, CR Lucas, KM Riedl… - Molecular nutrition & …, 2018 - Wiley Online Library
Bladder cancer is a significant health burden due to its high prevalence, risk of mortality,
morbidity, and high cost of medical care. Epidemiologic evidence suggests that diets rich in …

[HTML][HTML] Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease

MA Pappolla, G Perry, X Fang, M Zagorski… - Neurobiology of …, 2021 - Elsevier
Sporadic late-onset Alzheimer's disease (AD) is the most frequent cause of dementia
associated with aging. Due to the progressive aging of the population, AD is becoming a …

Sorting out the value of cruciferous sprouts as sources of bioactive compounds for nutrition and health

Á Abellán, R Domínguez-Perles, DA Moreno… - Nutrients, 2019 - mdpi.com
Edible sprouts with germinating seeds of a few days of age are naturally rich in nutrients and
other bioactive compounds. Among them, the cruciferous (Brassicaceae) sprouts stand out …

Using micropropagation to develop medicinal plants into crops

RM Moraes, AL Cerdeira, MV Lourenço - Molecules, 2021 - mdpi.com
Medicinal plants are still the major source of therapies for several illnesses and only part of
the herbal products originates from cultivated biomass. Wild harvests represent the major …

Anticancer effects of nutraceuticals in the Mediterranean diet: an epigenetic diet model

R Divella, A Daniele, E Savino… - Cancer Genomics & …, 2020 - cgp.iiarjournals.org
Epidemiological and clinical studies support the association between nutrition and
development or progression of different malignancies such as colon, breast, and prostate …

Influence of cooking methods on glucosinolates and isothiocyanates content in novel cruciferous foods

N Baenas, J Marhuenda, C García-Viguera, P Zafrilla… - Foods, 2019 - mdpi.com
Brassica vegetables are of great interest due to their antioxidant and anti-inflammatory
activity, being responsible for the glucosinolates (GLS) and their hydroxylated derivatives …