High‐frequency oscillations: the state of clinical research

B Frauscher, F Bartolomei, K Kobayashi… - …, 2017 - Wiley Online Library
Modern electroencephalographic (EEG) technology contributed to the appreciation that the
EEG signal outside the classical Berger frequency band contains important information. In …

Cross-frequency coupling and intelligent neuromodulation

CH Yeh, C Zhang, W Shi, MT Lo… - Cyborg and bionic …, 2023 - spj.science.org
Cross-frequency coupling (CFC) reflects (nonlinear) interactions between signals of different
frequencies. Evidence from both patient and healthy participant studies suggests that CFC …

Removing high-frequency oscillations: A prospective multicenter study on seizure outcome

J Jacobs, JY Wu, P Perucca, R Zelmann, M Mader… - Neurology, 2018 - AAN Enterprises
Objective To evaluate the use of interictal high-frequency oscillations (HFOs) in epilepsy
surgery for prediction of postsurgical seizure outcome in a prospective multicenter trial …

High‐frequency oscillations in the normal human brain

B Frauscher, N von Ellenrieder, R Zelmann… - Annals of …, 2018 - Wiley Online Library
Objective High‐frequency oscillations (HFOs) are a promising biomarker for the
epileptogenic zone. It has not been possible, however, to differentiate physiological from …

Developmental atlas of phase-amplitude coupling between physiologic high-frequency oscillations and slow waves

K Sakakura, N Kuroda, M Sonoda, T Mitsuhashi… - Nature …, 2023 - nature.com
We investigated the developmental changes in high-frequency oscillation (HFO) and
Modulation Index (MI)–the coupling measure between HFO and slow-wave phase. We …

Facilitation of epileptic activity during sleep is mediated by high amplitude slow waves

B Frauscher, N von Ellenrieder, T Ferrari-Marinho… - Brain, 2015 - academic.oup.com
Epileptic discharges in focal epilepsy are frequently activated during non-rapid eye
movement sleep. Sleep slow waves are present during this stage and have been shown to …

Focal resection of fast ripples on extraoperative intracranial EEG improves seizure outcome in pediatric epilepsy

T Akiyama, B McCoy, CY Go, A Ochi, IM Elliott… - …, 2011 - Wiley Online Library
Summary Purpose: High‐frequency oscillations (HFOs), termed ripples at 80–200 Hz and
fast ripples (FRs) at> 200/250 Hz, recorded by intracranial electroencephalography (EEG) …

Localization of the epileptogenic zone using high frequency oscillations

A Thomschewski, AS Hincapié, B Frauscher - Frontiers in neurology, 2019 - frontiersin.org
For patients with drug-resistant focal epilepsy, surgery is the therapy of choice in order to
achieve seizure freedom. Epilepsy surgery foremost requires the identification of the …

Ripple classification helps to localize the seizure‐onset zone in neocortical epilepsy

S Wang, IZ Wang, JC Bulacio, JC Mosher… - …, 2013 - Wiley Online Library
Purpose: Fast ripples are reported to be highly localizing to the epileptogenic or seizure‐
onset zone (SOZ) but may not be readily found in neocortical epilepsy, whereas ripples are …

Pathological and physiological high-frequency oscillations in focal human epilepsy

A Matsumoto, BH Brinkmann… - Journal of …, 2013 - journals.physiology.org
High-frequency oscillations (HFO; gamma: 40–100 Hz, ripples: 100–200 Hz, and fast
ripples: 250–500 Hz) have been widely studied in health and disease. These phenomena …