Peripheral arterial disease is a chronic vascular disease characterized by impaired
circulation to the lower extremities. Its most severe stage, known as critical limb ischemia …

Peripheral artery disease is an obstructive, atherosclerotic disease of the lower extremities
causing significant morbidity and mortality. Black Americans are disproportionately affected …

Peripheral artery disease (PAD) stems from atherosclerosis of lower extremity arteries with
resultant arterial narrowing or occlusion. The most severe form of PAD is termed chronic …

Background Critical limb ischemia (CLI) represents the most severe clinical manifestation of
peripheral arterial disease (PAD) and is the major cause of ischemic amputation in the …

Nontraumatic lower-extremity amputation is a devastating complication of peripheral artery
disease (PAD) with a high mortality and medical expenditure. There are≈ 150 000 …

Background Black race has been shown to be a risk factor for amputation in peripheral
artery disease (PAD); however, race has been argued to be a marker for socioeconomic …

Background Rates of major lower extremity amputation in patients with peripheral artery
disease are higher in rural communities with markers of low socioeconomic status, but most …

Peripheral artery disease (PAD), the pathophysiologic narrowing of arterial blood vessels of
the lower leg due to atherosclerosis, is a highly prevalent disease that affects more than 6 …

Most cases of lower extremity limb loss in the United States occur among people with
diabetes who have a diabetic foot ulcer (DFU). These DFUs and the associated limb loss …

METHODS: Protocol and registration This review was prospectively registered in the
Prospero International Prospective Register of Systematic Reviews (2018 ID …