[HTML][HTML] Trabecular meshwork cell differentiation in response to collagen and TGFβ-2 spatial interactions.

HC Lamont, AW Wright, K Devrie, KE Okur, M Jones… - Acta Biomaterialia, 2024 - Elsevier
Primary open angle glaucoma (POAG) is currently the most prevalent cause of irreversible
blindness globally. To date, there are few in vitro models that can faithfully recapitulate the …

m1A Regulatory gene signatures are associated with certain immune cell compositions of the tumor microenvironment and predict survival in kidney renal clear cell …

L Zhou, W Zhou, Y Li, R Hua - European Journal of Medical Research, 2023 - Springer
Adenosine N1 methylation (m1A) of RNA, a type of post-transcriptional modification, has
been shown to play a significant role in the progression of cancer. The objective of the …

[HTML][HTML] Dexmedetomidine ameliorates high glucose-induced epithelial-mesenchymal transformation in HK-2 cells through the Cdk5/Drp1/ROS pathway …

F Wang, W Xu, X Liu, J Zhang - Acta Biochimica et Biophysica …, 2024 - ncbi.nlm.nih.gov
Epithelial-mesenchymal transformation (EMT) plays an important role in the progression of
diabetic nephropathy. Dexmedetomidine (DEX) has shown renoprotective effects against …

Utilizing gene co-expression networks with the rat kidney TXG-MAPr tool to enhance safety assessment, biomarker identification and human translation

SJ Kunnen, G Callegaro, JJ Sutherland… - bioRxiv, 2023 - biorxiv.org
Toxicogenomic data represent a valuable source of biological information at molecular and
cellular level to understand unanticipated organ toxicities. Weighted gene co-expression …