CRNDE: a long non-coding RNA involved in C ance R, N eurobiology, and DE velopment

BC Ellis, PL Molloy, LD Graham - Frontiers in genetics, 2012 - frontiersin.org
CRNDE is the gene symbol for Colorectal Neoplasia Differentially Expressed (non-protein-
coding), a long non-coding RNA (lncRNA) gene that expresses multiple splice variants and …

The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt/β-catenin signaling

P Han, J Li, B Zhang, J Lv, Y Li, X Gu, Z Yu, Y Jia, X Bai… - Molecular cancer, 2017 - Springer
Background With more than 600,000 mortalities each year, colorectal cancer (CRC) is the
third most commonly diagnosed type of cancer worldwide. Recently, mechanisms involving …

Uromodulin biology and pathophysiology–an update

P Vyletal, AJ Bleyer, S Kmoch - Kidney and Blood Pressure Research, 2010 - karger.com
Uromodulin (UMOD) is a glycoprotein expressed on the luminal surface of the apical
membrane of renal tubular epithelial cells forming the thick ascending limb of Henle. Here …

Contemporary epidemiology of renal cell cancer

WH Chow, SS Devesa - The Cancer Journal, 2008 - journals.lww.com
We analyzed renal cell cancer incidence patterns in the United States and reviewed recent
epidemiologic evidence with regard to environmental and host genetic determinants of renal …

Neuronal pentraxin 2 supports clear cell renal cell carcinoma by activating the AMPA-selective glutamate receptor-4

CA Von Roemeling, DC Radisky, LA Marlow… - Cancer research, 2014 - AACR
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer and
has the highest propensity to manifest as metastatic disease. Recent characterizations of the …

Lactate dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma

H Girgis, O Masui, NMA White, A Scorilas, F Rotondo… - Molecular cancer, 2014 - Springer
Background Over 90% of cancer-related deaths in clear cell renal cell carcinoma (RCC) are
caused by tumor relapse and metastasis. Thus, there is an urgent need for new molecular …

CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug

Y Liang, J Cen, Y Huang, Y Fang, Y Wang, G Shu… - Molecular cancer, 2022 - Springer
Background Recent studies have identified that circular RNAs (circRNAs) have an important
role in cancer via their well-recognized sponge effect on miRNAs, which regulates a large …

Differential protein profiling of renal cell carcinoma urinary exosomes

F Raimondo, L Morosi, S Corbetta, C Chinello… - Molecular …, 2013 - pubs.rsc.org
Renal cell carcinoma (RCC) accounts for about 3% of all human malignancies and its
incidence is increasing. There are no standard biomarkers currently used in the clinical …

Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors

T Wrzesiński, M Szelag, WA Cieślikowski, A Ida… - BMC cancer, 2015 - Springer
Background VHL inactivation is the most established molecular characteristic of clear cell
renal cell carcinoma (ccRCC), with only a few additional genes implicated in development of …

Increased expression of the long noncoding RNA CRNDE-h indicates a poor prognosis in colorectal cancer, and is positively correlated with IRX5 mRNA expression

T Liu, Y Yang, L Du, C Wang - OncoTargets and therapy, 2016 - Taylor & Francis
Background The long noncoding RNA (lncRNA) colorectal neoplasia differentially
expressed–h (CRNDE-h) plays important roles in the early stages of human development …